6bm8
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of glycoprotein B from Herpes Simplex Virus type I== | |
| - | + | <StructureSection load='6bm8' size='340' side='right' caption='[[6bm8]], [[Resolution|resolution]] 4.10Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6bm8]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6BM8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6BM8 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr> | |
| - | [[Category: | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5v2s|5v2s]]</td></tr> |
| - | [[Category: Heldwein, E | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6bm8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6bm8 OCA], [http://pdbe.org/6bm8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6bm8 RCSB], [http://www.ebi.ac.uk/pdbsum/6bm8 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6bm8 ProSAT]</span></td></tr> |
| - | [[Category: | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/A1Z0P7_HHV1 A1Z0P7_HHV1]] Envelope glycoprotein that forms spikes at the surface of virion envelope. Essential for the initial attachment to heparan sulfate moities of the host cell surface proteoglycans. Involved in fusion of viral and cellular membranes leading to virus entry into the host cell. Following initial binding to its host receptors, membrane fusion is mediated by the fusion machinery composed at least of gB and the heterodimer gH/gL. May be involved in the fusion between the virion envelope and the outer nuclear membrane during virion egress.[HAMAP-Rule:MF_04032] | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Cooper, R S]] | ||
| + | [[Category: Heldwein, E E]] | ||
| + | [[Category: Bitopic membrane protein]] | ||
| + | [[Category: Fusogen]] | ||
| + | [[Category: Viral protein]] | ||
Revision as of 05:29, 16 May 2018
Crystal structure of glycoprotein B from Herpes Simplex Virus type I
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