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6fu7
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==ATP phosphoribosyltransferase (HisZG ATPPRT) from Psychrobacter arcticus in complex with PRATP== | |
| - | + | <StructureSection load='6fu7' size='340' side='right' caption='[[6fu7]], [[Resolution|resolution]] 2.31Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6fu7]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6FU7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6FU7 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PRT:PHOSPHORIBOSYL+ATP'>PRT</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr> | |
| - | [[Category: | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/ATP_phosphoribosyltransferase ATP phosphoribosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.17 2.4.2.17] </span></td></tr> |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6fu7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6fu7 OCA], [http://pdbe.org/6fu7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6fu7 RCSB], [http://www.ebi.ac.uk/pdbsum/6fu7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6fu7 ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/HISZ_PSYA2 HISZ_PSYA2]] Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.[HAMAP-Rule:MF_00125] [[http://www.uniprot.org/uniprot/HIS1_PSYA2 HIS1_PSYA2]] Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: ATP phosphoribosyltransferase]] | ||
| + | [[Category: Alphey, M S]] | ||
| + | [[Category: Czekster, C M]] | ||
[[Category: Fisher, G]] | [[Category: Fisher, G]] | ||
[[Category: Ge, Y]] | [[Category: Ge, Y]] | ||
| - | [[Category: | + | [[Category: Naismith, J H]] |
| - | [[Category: | + | [[Category: Silva, R G.da]] |
| - | [[Category: | + | [[Category: Atp phosphoribosyltransferase]] |
| + | [[Category: Cold-adapted]] | ||
| + | [[Category: Hiszg]] | ||
| + | [[Category: Transferase]] | ||
Current revision
ATP phosphoribosyltransferase (HisZG ATPPRT) from Psychrobacter arcticus in complex with PRATP
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