Alice Clark/ATPsynthase
From Proteopedia
(Difference between revisions)
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<StructureSection load='5lqz' size='350' side='right' caption='ATP Synthase (PDB entry [[5lqz]])' scene=''> | <StructureSection load='5lqz' size='350' side='right' caption='ATP Synthase (PDB entry [[5lqz]])' scene=''> | ||
| + | Exploring in 3D | ||
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| + | - left mouse button to rotate the protein model. | ||
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| + | - middle mouse button or scroll wheel to zoom (option-click on a Mac) | ||
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| + | - right mouse button for more options and information (control-click on a Mac). | ||
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| + | Have a go yourself now ==> | ||
The synthesis of ATP involves a number of steps | The synthesis of ATP involves a number of steps | ||
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3. Releasing the newly made ATP | 3. Releasing the newly made ATP | ||
| - | These steps are performed by a tiny motor, found in the mitochondrial membrane, called ATP synthase | + | These steps are performed by a tiny motor, found in the mitochondrial membrane, called ATP synthase - shown here in 3D. |
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| - | The axle rotates putting the motor into three different conformations as the ADP binds, the phosphate bond is formed and the ATP being released. | + | The <scene name='78/781973/Axel/1'>axle</scene> rotates putting the motor into three different conformations as the ADP binds, the phosphate bond is formed and the ATP being released. |
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The F0 is a circular rotor that is formed of alpha helices that sit in the mitochondrial membrane. The hydrogen ions travel around the circular F0 motor, and turning the rotor in the process, much like a water wheel. The hydrogens are passed alone a chain of aspartic acid residues (amino acids) in the F0 motor, and then transferred to an arginine amino acid. The arginine passes the hydrogen to the rotor, which turns all the way around. Then the hydrogen is then passed to the opposite side of the membrane. | The F0 is a circular rotor that is formed of alpha helices that sit in the mitochondrial membrane. The hydrogen ions travel around the circular F0 motor, and turning the rotor in the process, much like a water wheel. The hydrogens are passed alone a chain of aspartic acid residues (amino acids) in the F0 motor, and then transferred to an arginine amino acid. The arginine passes the hydrogen to the rotor, which turns all the way around. Then the hydrogen is then passed to the opposite side of the membrane. | ||
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To the right is a structure of ATP synthase shown using the Jmol viewer within [http://proteopedia.org/wiki/index.php/Main_Page Proteopedia]. | To the right is a structure of ATP synthase shown using the Jmol viewer within [http://proteopedia.org/wiki/index.php/Main_Page Proteopedia]. | ||
| - | |||
| - | |||
| - | Exploring in 3D | ||
| - | |||
| - | - left mouse button to rotate the protein model. | ||
| - | |||
| - | - middle mouse button or scroll wheel to zoom (option-click on a Mac) | ||
| - | |||
| - | - right mouse button for more options and information (control-click on a Mac). | ||
| - | |||
| - | Have a go yourself now ==> | ||
Revision as of 13:12, 10 March 2018
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ATP Synthase
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