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2fk6

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[[Image:2fk6.gif|left|200px]]
[[Image:2fk6.gif|left|200px]]
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{{Structure
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<!--
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|PDB= 2fk6 |SIZE=350|CAPTION= <scene name='initialview01'>2fk6</scene>, resolution 2.90&Aring;
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The line below this paragraph, containing "STRUCTURE_2fk6", creates the "Structure Box" on the page.
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|SITE=
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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|LIGAND= <scene name='pdbligand=A:ADENOSINE-5&#39;-MONOPHOSPHATE'>A</scene>, <scene name='pdbligand=C:CYTIDINE-5&#39;-MONOPHOSPHATE'>C</scene>, <scene name='pdbligand=G:GUANOSINE-5&#39;-MONOPHOSPHATE'>G</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=U:URIDINE-5&#39;-MONOPHOSPHATE'>U</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Ribonuclease_Z Ribonuclease Z], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.26.11 3.1.26.11] </span>
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or leave the SCENE parameter empty for the default display.
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|GENE= RNZ ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1423 Bacillus subtilis])
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-->
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|DOMAIN=
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{{STRUCTURE_2fk6| PDB=2fk6 | SCENE= }}
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|RELATEDENTRY=[[1y44|1Y44]], [[1ww1|1WW1]]
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2fk6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fk6 OCA], [http://www.ebi.ac.uk/pdbsum/2fk6 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2fk6 RCSB]</span>
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}}
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'''Crystal Structure of RNAse Z/tRNA(Thr) complex'''
'''Crystal Structure of RNAse Z/tRNA(Thr) complex'''
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[[Category: Pellegrini, O.]]
[[Category: Pellegrini, O.]]
[[Category: Sierra-Gallay, I Li de la.]]
[[Category: Sierra-Gallay, I Li de la.]]
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[[Category: protein-trna complex]]
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[[Category: Protein-trna complex]]
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[[Category: trna maturase]]
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[[Category: Trna maturase]]
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[[Category: zinc-dependent metal hydrolase]]
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[[Category: Zinc-dependent metal hydrolase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May 4 03:59:30 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 03:03:55 2008''
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Revision as of 00:59, 4 May 2008

Image:2fk6.gif

Template:STRUCTURE 2fk6

Crystal Structure of RNAse Z/tRNA(Thr) complex


Overview

The highly conserved ribonuclease RNase Z catalyzes the endonucleolytic removal of the 3' extension of the majority of tRNA precursors. Here we present the structure of the complex between Bacillus subtilis RNase Z and tRNA(Thr), the first structure of a ribonucleolytic processing enzyme bound to tRNA. Binding of tRNA to RNase Z causes conformational changes in both partners to promote reorganization of the catalytic site and tRNA cleavage.

About this Structure

2FK6 is a Protein complex structure of sequences from Bacillus subtilis. Full crystallographic information is available from OCA.

Reference

Structure of the ubiquitous 3' processing enzyme RNase Z bound to transfer RNA., Li de la Sierra-Gallay I, Mathy N, Pellegrini O, Condon C, Nat Struct Mol Biol. 2006 Apr;13(4):376-7. Epub 2006 Mar 5. PMID:16518398 Page seeded by OCA on Sun May 4 03:59:30 2008

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