2fk6
From Proteopedia
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[[Image:2fk6.gif|left|200px]] | [[Image:2fk6.gif|left|200px]] | ||
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'''Crystal Structure of RNAse Z/tRNA(Thr) complex''' | '''Crystal Structure of RNAse Z/tRNA(Thr) complex''' | ||
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[[Category: Pellegrini, O.]] | [[Category: Pellegrini, O.]] | ||
[[Category: Sierra-Gallay, I Li de la.]] | [[Category: Sierra-Gallay, I Li de la.]] | ||
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- | [[Category: | + | [[Category: Zinc-dependent metal hydrolase]] |
- | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May 4 03:59:30 2008'' | |
- | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + |
Revision as of 00:59, 4 May 2008
Crystal Structure of RNAse Z/tRNA(Thr) complex
Overview
The highly conserved ribonuclease RNase Z catalyzes the endonucleolytic removal of the 3' extension of the majority of tRNA precursors. Here we present the structure of the complex between Bacillus subtilis RNase Z and tRNA(Thr), the first structure of a ribonucleolytic processing enzyme bound to tRNA. Binding of tRNA to RNase Z causes conformational changes in both partners to promote reorganization of the catalytic site and tRNA cleavage.
About this Structure
2FK6 is a Protein complex structure of sequences from Bacillus subtilis. Full crystallographic information is available from OCA.
Reference
Structure of the ubiquitous 3' processing enzyme RNase Z bound to transfer RNA., Li de la Sierra-Gallay I, Mathy N, Pellegrini O, Condon C, Nat Struct Mol Biol. 2006 Apr;13(4):376-7. Epub 2006 Mar 5. PMID:16518398 Page seeded by OCA on Sun May 4 03:59:30 2008