5zic
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of human GnT-V luminal domain in complex with acceptor sugar== | |
| - | + | <StructureSection load='5zic' size='340' side='right' caption='[[5zic]], [[Resolution|resolution]] 2.10Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5zic]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ZIC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ZIC FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=Z4Y:6-thio-alpha-D-mannopyranose'>Z4Y</scene></td></tr> | |
| - | [[Category: | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5zib|5zib]]</td></tr> |
| + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Alpha-1,6-mannosyl-glycoprotein_6-beta-N-acetylglucosaminyltransferase Alpha-1,6-mannosyl-glycoprotein 6-beta-N-acetylglucosaminyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.1.155 2.4.1.155] </span></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5zic FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5zic OCA], [http://pdbe.org/5zic PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5zic RCSB], [http://www.ebi.ac.uk/pdbsum/5zic PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5zic ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/MGT5A_HUMAN MGT5A_HUMAN]] Catalyzes the addition of N-acetylglucosamine in beta 1-6 linkage to the alpha-linked mannose of biantennary N-linked oligosaccharides. It is one of the most important enzymes involved in the regulation of the biosynthesis of glycoprotein oligosaccharides. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Alpha-1,6-mannosyl-glycoprotein 6-beta-N-acetylglucosaminyltransferase]] | ||
| + | [[Category: Nagae, M]] | ||
| + | [[Category: Yamaguchi, Y]] | ||
| + | [[Category: Glycosyltransferase cancer metastasis luminal protein]] | ||
| + | [[Category: Sugar binding protein]] | ||
Revision as of 18:40, 1 August 2018
Crystal structure of human GnT-V luminal domain in complex with acceptor sugar
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