This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
6cjp
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Candida albicans Hsp90 nucleotide binding domain in complex with radicicol== | |
| - | + | <StructureSection load='6cjp' size='340' side='right' caption='[[6cjp]], [[Resolution|resolution]] 2.60Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6cjp]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6CJP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6CJP FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=F5S:(1aR,2Z,4E,6E,14R,15aR)-9,11-dihydroxy-6-{[(4-methoxyphenyl)methoxy]imino}-14-methyl-1a,6,7,14,15,15a-hexahydro-12H-oxireno[e][2]benzoxacyclotetradecin-12-one'>F5S</scene></td></tr> | |
| - | [[ | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[6cji|6cji]], [[6cjj|6cjj]], [[6cjl|6cjl]]</td></tr> |
| - | [[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6cjp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6cjp OCA], [http://pdbe.org/6cjp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6cjp RCSB], [http://www.ebi.ac.uk/pdbsum/6cjp PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6cjp ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/HSP90_CANAL HSP90_CANAL]] Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function (By similarity). | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Nation, C]] | [[Category: Nation, C]] | ||
| + | [[Category: Pizarro, J C]] | ||
| + | [[Category: Chaperone]] | ||
| + | [[Category: Hsp90. atpase]] | ||
Revision as of 08:14, 30 January 2019
Candida albicans Hsp90 nucleotide binding domain in complex with radicicol
| |||||||||||
