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Bromodomain-containing protein

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**[[4kv1]] – hBRD4 bromodomain 1 + Rel peptide<br />
**[[4kv1]] – hBRD4 bromodomain 1 + Rel peptide<br />
**[[3mxf]] – mBRD4 bromodomain 1 + inhibitor<br />
**[[3mxf]] – mBRD4 bromodomain 1 + inhibitor<br />
-
**[[3p5o]], [[2yel]], [[3zyu]], [[3u5j]], [[3u5k]], [[3u5l]], [[4a9l]], [[4e96]], [[4f3i]], [[4hxk]], [[4hxl]], [[4hxm]], [[4hxn]], [[4hxo]], [[4hxp]], [[4hxr]], [[4hxs]], [[4lr6]], [[4lrg]], [[3svf]], [[3svg]], [[4gpj]], [[4hbv]], [[4hbw]], [[4hbx]], [[4hby]], [[4don]], [[4j0r]], [[4j0s]], [[4bw1]], [[4bw2]], [[4bw3]], [[4bw4]], [[4men]], [[4meo]], [[4mep]], [[4meq]], [[4bjx]], [[4c66]], [[4c67]], [[4ioo]], [[4ioq]], [[4ior]], [[4mr3]], [[4mr4]], [[4nqm]], [[4nr8]], [[4cfk]], [[4cfl]], [[4lyw]], [[4ogi]], [[4ogj]], [[4o70]], [[4o71]], [[4o72]], [[4o74]], [[4o75]], [[4o76]], [[4o77]], [[4o78]], [[4o7a]], [[4o7b]], [[4o7c]], [[4o7e]], [[4o7f]], [[4ps5]], [[4nuc]], [[4nue]], [[4nud]], [[4pce]], [[4pci]], [[4uyd]], [[4qzs]], [[4wiv]], [[4cl9]], [[4clb]], [[4xy9]], [[4xya]], [[4z1q]], [[4z1s]], [[4uix]], [[4uiy]], [[4uiz]], [[4qr3]], [[4qr4]], [[4qr5]], [[5bt4]], [[5a5s]], [[5a85]], [[5acy]], [[4x2i]], [[4zc9]], [[5fbx]], [[4yh3]], [[4yh4]], [[5coi]], [[5cp5]], [[5cpe]], [[5cqt]], [[5crm]], [[5crz]], [[5cs8]], [[5ctl]], [[5cy9]], [[5d0c]], [[5dx4]], [[4lzs]], [[5d24]], [[5d25]], [[5d26]], [[5d3h]], [[5d3j]], [[5d3l]], [[5d3n]], [[5d3p]], [[5d3r]], [[5d3s]], [[5d3t]], [[5egu]], [[5ei4]], [[5eis]], [[5hls]], [[5hm0]], [[5ku3]], [[5khm]], [[5i88]], [[5i80]], [[5f63]], [[5f62]], [[5f61]], [[5f60]], [[5e0r]], [[5dw2]], [[5dlz]], [[5dlx]], [[5cfw]], [[5ad3]], [[5ad2]], [[4zw1]], [[5u2f]], [[5u2e]], [[5u28]], [[5luu]], [[5lj2]], [[5lj1]], [[5y1y]], [[5wuu]], [[5vom]], [[5v67]], [[5uvw]], [[5ula]], [[5ti7]], [[5n2m]], [[5mli], [[5mkz]]], [[5m3a]], [[5m39]], [[5lrq]], [[5kj0]], [[5kdh]], [[5h21]], [[5f5z]] – hBRD4 bromodomain 1 + inhibitor<br />
+
**[[3p5o]], [[2yel]], [[3zyu]], [[3u5j]], [[3u5k]], [[3u5l]], [[4a9l]], [[4e96]], [[4f3i]], [[4hxk]], [[4hxl]], [[4hxm]], [[4hxn]], [[4hxo]], [[4hxp]], [[4hxr]], [[4hxs]], [[4lr6]], [[4lrg]], [[3svf]], [[3svg]], [[4gpj]], [[4hbv]], [[4hbw]], [[4hbx]], [[4hby]], [[4don]], [[4j0r]], [[4j0s]], [[4bw1]], [[4bw2]], [[4bw3]], [[4bw4]], [[4men]], [[4meo]], [[4mep]], [[4meq]], [[4bjx]], [[4c66]], [[4c67]], [[4ioo]], [[4ioq]], [[4ior]], [[4mr3]], [[4mr4]], [[4nqm]], [[4nr8]], [[4cfk]], [[4cfl]], [[4lyw]], [[4ogi]], [[4ogj]], [[4o70]], [[4o71]], [[4o72]], [[4o74]], [[4o75]], [[4o76]], [[4o77]], [[4o78]], [[4o7a]], [[4o7b]], [[4o7c]], [[4o7e]], [[4o7f]], [[4ps5]], [[4nuc]], [[4nue]], [[4nud]], [[4pce]], [[4pci]], [[4uyd]], [[4qzs]], [[4wiv]], [[4cl9]], [[4clb]], [[4xy9]], [[4xya]], [[4z1q]], [[4z1s]], [[4uix]], [[4uiy]], [[4uiz]], [[4qr3]], [[4qr4]], [[4qr5]], [[5bt4]], [[5a5s]], [[5a85]], [[5acy]], [[4x2i]], [[4zc9]], [[5fbx]], [[4yh3]], [[4yh4]], [[5coi]], [[5cp5]], [[5cpe]], [[5cqt]], [[5crm]], [[5crz]], [[5cs8]], [[5ctl]], [[5cy9]], [[5d0c]], [[5dx4]], [[4lzs]], [[5d24]], [[5d25]], [[5d26]], [[5d3h]], [[5d3j]], [[5d3l]], [[5d3n]], [[5d3p]], [[5d3r]], [[5d3s]], [[5d3t]], [[5egu]], [[5ei4]], [[5eis]], [[5hls]], [[5hm0]], [[5ku3]], [[5khm]], [[5i88]], [[5i80]], [[5f63]], [[5f62]], [[5f61]], [[5f60]], [[5e0r]], [[5dw2]], [[5dlz]], [[5dlx]], [[5cfw]], [[5ad3]], [[5ad2]], [[4zw1]], [[5u2f]], [[5u2e]], [[5u28]], [[5luu]], [[5lj2]], [[5lj1]], [[5y1y]], [[5wuu]], [[5vom]], [[5v67]], [[5uvw]], [[5ula]], [[5ti7]], [[5n2m]], [[5mli]], [[5mkz]]], [[5m3a]], [[5m39]], [[5lrq]], [[5kj0]], [[5kdh]], [[5h21]], [[5f5z]] – hBRD4 bromodomain 1 + inhibitor<br />
**[[5z9c]] – hBRD4 bromodomain 1 + inhibitor - NMR<br />
**[[5z9c]] – hBRD4 bromodomain 1 + inhibitor - NMR<br />
**[[5ti6]], [[5ti5]], [[5ti4]], [[5ti3]], [[5ti2]] – hBRD4 bromodomain 1 (mutant) + inhibitor <br />
**[[5ti6]], [[5ti5]], [[5ti4]], [[5ti3]], [[5ti2]] – hBRD4 bromodomain 1 (mutant) + inhibitor <br />

Revision as of 10:04, 3 April 2018

Human bromodomain-containing protein 4 bromodomain 1 complex with inhibitor and ethylene glycol (PDB code 3p5o)

Drag the structure with the mouse to rotate

3D Structures of bromodomain-containing protein

Updated on 03-April-2018


References

  1. ↑ Zeng L, Zhou MM. Bromodomain: an acetyl-lysine binding domain. FEBS Lett. 2002 Feb 20;513(1):124-8. PMID:11911891
  2. ↑ Belkina AC, Denis GV. BET domain co-regulators in obesity, inflammation and cancer. Nat Rev Cancer. 2012 Jun 22;12(7):465-77. doi: 10.1038/nrc3256. PMID:22722403 doi:http://dx.doi.org/10.1038/nrc3256
  3. ↑ French CA. Demystified molecular pathology of NUT midline carcinomas. J Clin Pathol. 2010 Jun;63(6):492-6. doi: 10.1136/jcp.2007.052902. Epub 2008 Jun , 13. PMID:18552174 doi:http://dx.doi.org/10.1136/jcp.2007.052902
  4. ↑ French CA. Demystified molecular pathology of NUT midline carcinomas. J Clin Pathol. 2010 Jun;63(6):492-6. doi: 10.1136/jcp.2007.052902. Epub 2008 Jun , 13. PMID:18552174 doi:http://dx.doi.org/10.1136/jcp.2007.052902

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Michal Harel, Alexander Berchansky, Joel L. Sussman

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