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Bromodomain-containing protein

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== Structural highlights ==
== Structural highlights ==
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<scene name='72/724778/Cv/3'>BRD4 bromodomain 1 inhibitors bind to the acetyl-binding pocket</scene><ref>PMID:18552174</ref>.
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<scene name='72/724778/Cv/3'>BRD4 bromodomain 1 inhibitors bind to the acetyl-binding pocket</scene><ref>PMID:18552174</ref>. Water molecules are shown as red spheres.
</StructureSection>
</StructureSection>

Revision as of 11:33, 27 May 2018

Human bromodomain-containing protein 4 bromodomain 1 complex with inhibitor and ethylene glycol (PDB code 3p5o)

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3D Structures of bromodomain-containing protein

Updated on 27-May-2018


References

  1. ↑ Zeng L, Zhou MM. Bromodomain: an acetyl-lysine binding domain. FEBS Lett. 2002 Feb 20;513(1):124-8. PMID:11911891
  2. ↑ Belkina AC, Denis GV. BET domain co-regulators in obesity, inflammation and cancer. Nat Rev Cancer. 2012 Jun 22;12(7):465-77. doi: 10.1038/nrc3256. PMID:22722403 doi:http://dx.doi.org/10.1038/nrc3256
  3. ↑ French CA. Demystified molecular pathology of NUT midline carcinomas. J Clin Pathol. 2010 Jun;63(6):492-6. doi: 10.1136/jcp.2007.052902. Epub 2008 Jun , 13. PMID:18552174 doi:http://dx.doi.org/10.1136/jcp.2007.052902
  4. ↑ French CA. Demystified molecular pathology of NUT midline carcinomas. J Clin Pathol. 2010 Jun;63(6):492-6. doi: 10.1136/jcp.2007.052902. Epub 2008 Jun , 13. PMID:18552174 doi:http://dx.doi.org/10.1136/jcp.2007.052902

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