This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
5zbq
From Proteopedia
(Difference between revisions)
m (Protected "5zbq" [edit=sysop:move=sysop]) |
|||
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | The | + | ==The Crystal Structure of human neuropeptide Y Y1 receptor with UR-MK299== |
| - | + | <StructureSection load='5zbq' size='340' side='right' caption='[[5zbq]], [[Resolution|resolution]] 2.70Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5zbq]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ZBQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ZBQ FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=9AO:N~2~-(diphenylacetyl)-N-[(4-hydroxyphenyl)methyl]-N~5~-(N-{[2-(propanoylamino)ethyl]carbamoyl}carbamimidoyl)-D-ornithinamide'>9AO</scene></td></tr> | |
| - | [[Category: | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5zbh|5zbh]]</td></tr> |
| + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5zbq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5zbq OCA], [http://pdbe.org/5zbq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5zbq RCSB], [http://www.ebi.ac.uk/pdbsum/5zbq PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5zbq ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/NPY1R_HUMAN NPY1R_HUMAN]] Receptor for neuropeptide Y and peptide YY. The rank order of affinity of this receptor for pancreatic polypeptides is NPY > [Pro-34] PYY, PYY and [Leu-31, Pro-34] NPY > NPY (2-36) > [Ile-31, Gln-34] PP and PYY (3-36) > PP > NPY free acid. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Lysozyme]] | ||
| + | [[Category: Han, S]] | ||
[[Category: Wu, B]] | [[Category: Wu, B]] | ||
[[Category: Yang, Z]] | [[Category: Yang, Z]] | ||
| - | [[Category: Han, S]] | ||
[[Category: Zhao, Q]] | [[Category: Zhao, Q]] | ||
| + | [[Category: Complex structure]] | ||
| + | [[Category: G protein-coupled receptor]] | ||
| + | [[Category: Receptor inhibitor]] | ||
| + | [[Category: Signaling protein]] | ||
Revision as of 05:31, 25 April 2018
The Crystal Structure of human neuropeptide Y Y1 receptor with UR-MK299
| |||||||||||
