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5ost
From Proteopedia
(Difference between revisions)
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<StructureSection load='5ost' size='340' side='right' caption='[[5ost]], [[Resolution|resolution]] 2.10Å' scene=''> | <StructureSection load='5ost' size='340' side='right' caption='[[5ost]], [[Resolution|resolution]] 2.10Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[5ost]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5OST OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5OST FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[5ost]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Thexl Thexl]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5OST OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5OST FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AEZ:(4~{S},5~{S},6~{R},7~{R})-7-(hydroxymethyl)-4,5,6,7-tetrahydro-1~{H}-benzimidazole-4,5,6-triol'>AEZ</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AEZ:(4~{S},5~{S},6~{R},7~{R})-7-(hydroxymethyl)-4,5,6,7-tetrahydro-1~{H}-benzimidazole-4,5,6-triol'>AEZ</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Thexy_2211 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=858215 THEXL])</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucosylceramidase Glucosylceramidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.45 3.2.1.45] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucosylceramidase Glucosylceramidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.45 3.2.1.45] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ost FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ost OCA], [http://pdbe.org/5ost PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ost RCSB], [http://www.ebi.ac.uk/pdbsum/5ost PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ost ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ost FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ost OCA], [http://pdbe.org/5ost PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ost RCSB], [http://www.ebi.ac.uk/pdbsum/5ost PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ost ProSAT]</span></td></tr> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Glucosylceramidase]] | [[Category: Glucosylceramidase]] | ||
| + | [[Category: Thexl]] | ||
[[Category: Davies, G J]] | [[Category: Davies, G J]] | ||
[[Category: Offen, W A]] | [[Category: Offen, W A]] | ||
[[Category: Hydrolase]] | [[Category: Hydrolase]] | ||
Revision as of 05:52, 25 April 2018
A New Class of Beta-glucosidase inhibitor
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