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Core-binding factor

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*Core-binding factor β subunit
*Core-binding factor β subunit
-
**[[1ilf]], [[2jhb]] – mCBFb<br />
+
**[[4n9f]] – hCBFb + cullin-5 + elongin-B + virion infectivity factor<br />
-
**[[4n9f]] – hCBFb + cullin-5 + transcription elongation factor B + virion infectivity factor<br />
+
**[[6p59]] – hCBFb + elongin-B + elongin-C + virion infectivity factor<br />
 +
**[[6nil]] – hCBFb + A3F complex + virion infectivity factor – Cryo EM<br />
 +
**[[1ilf]] – mCBFb<br />
*Core-binding factor α+β subunits
*Core-binding factor α+β subunits

Revision as of 08:31, 7 July 2020

Human CBFα runt domain (magenta) complex with CBFβ heterodimerization domain (green) and DNA (PDB code 1h9d)

Drag the structure with the mouse to rotate

3D Structures of core-binding factor

Updated on 07-July-2020


References

  1. ↑ Bravo J, Li Z, Speck NA, Warren AJ. The leukemia-associated AML1 (Runx1)--CBF beta complex functions as a DNA-induced molecular clamp. Nat Struct Biol. 2001 Apr;8(4):371-8. PMID:11276260 doi:http://dx.doi.org/10.1038/86264

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Michal Harel, Joel L. Sussman, Alexander Berchansky

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