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6d1x

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m (Protected "6d1x" [edit=sysop:move=sysop])
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'''Unreleased structure'''
 
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The entry 6d1x is ON HOLD
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==N-Domain Of Grp94, with the Charged Domain, In Complex With the Novel Ligand N-Propyl Carboxyamido Adenosine==
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<StructureSection load='6d1x' size='340' side='right' caption='[[6d1x]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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Authors: Gewirth, D.T., Immormino, R.M.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[6d1x]] is a 1 chain structure. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1u0y 1u0y]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6D1X OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6D1X FirstGlance]. <br>
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Description: N-Domain Of Grp94, with the Charged Domain, In Complex With the Novel Ligand N-Propyl Carboxyamido Adenosine
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PA7:N-PROPYL+CARBOXYAMIDO+ADENOSINE'>PA7</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6d1x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6d1x OCA], [http://pdbe.org/6d1x PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6d1x RCSB], [http://www.ebi.ac.uk/pdbsum/6d1x PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6d1x ProSAT]</span></td></tr>
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[[Category: Immormino, R.M]]
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</table>
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[[Category: Gewirth, D.T]]
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== Function ==
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[[http://www.uniprot.org/uniprot/ENPL_CANLF ENPL_CANLF]] Molecular chaperone that functions in the processing and transport of secreted proteins. When associated with CNPY3, required for proper folding of Toll-like receptors. Functions in endoplasmic reticulum associated degradation (ERAD). Has ATPase activity (By similarity).
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__TOC__
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</StructureSection>
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[[Category: Gewirth, D T]]
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[[Category: Immormino, R M]]
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[[Category: Chaperone]]
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[[Category: Co-crystal]]
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[[Category: Hsp90]]
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[[Category: Inhibitor]]

Revision as of 07:53, 2 May 2018

N-Domain Of Grp94, with the Charged Domain, In Complex With the Novel Ligand N-Propyl Carboxyamido Adenosine

6d1x, resolution 2.30Å

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