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6d23
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==GLUCOSE-6-P DEHYDROGENASE (APO FORM) FROM TRYPANOSOMA CRUZI== | |
| + | <StructureSection load='6d23' size='340' side='right' caption='[[6d23]], [[Resolution|resolution]] 2.85Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[6d23]] is a 4 chain structure. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=4e9i 4e9i]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6D23 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6D23 FirstGlance]. <br> | ||
| + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
| + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucose-6-phosphate_dehydrogenase Glucose-6-phosphate dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.49 1.1.1.49] </span></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6d23 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6d23 OCA], [http://pdbe.org/6d23 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6d23 RCSB], [http://www.ebi.ac.uk/pdbsum/6d23 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6d23 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | An N-terminally truncated version of the enzyme glucose-6-phosphate dehydrogenase from Trypanosoma cruzi lacking the first 37 residues was crystallized both in its apo form and in a binary complex with glucose 6-phosphate. The crystals both belonged to space group P2(1) and diffracted to 2.85 and 3.35 A resolution, respectively. Self-rotation function maps were consistent with point group 222. The structure was solved by molecular replacement, confirming a tetrameric quaternary structure. | ||
| - | + | Expression, crystallization and preliminary X-ray crystallographic analysis of glucose-6-phosphate dehydrogenase from the human pathogen Trypanosoma cruzi in complex with substrate.,Ortiz C, Larrieux N, Medeiros A, Botti H, Comini M, Buschiazzo A Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011 Nov 1;67(Pt 11):1457-61., Epub 2011 Oct 27. PMID:22102256<ref>PMID:22102256</ref> | |
| - | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |
| - | + | </div> | |
| - | [[Category: | + | <div class="pdbe-citations 6d23" style="background-color:#fffaf0;"></div> |
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Glucose-6-phosphate dehydrogenase]] | ||
[[Category: Botti, H]] | [[Category: Botti, H]] | ||
| + | [[Category: Buschiazzo, A]] | ||
| + | [[Category: Comini, M A]] | ||
[[Category: Ortiz, C]] | [[Category: Ortiz, C]] | ||
| - | [[Category: | + | [[Category: Alpha beta]] |
| + | [[Category: Dehydrogenase]] | ||
| + | [[Category: Oxidoreductase]] | ||
| + | [[Category: Pentose phosphate pathway]] | ||
Revision as of 07:53, 2 May 2018
GLUCOSE-6-P DEHYDROGENASE (APO FORM) FROM TRYPANOSOMA CRUZI
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