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6g78

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'''Unreleased structure'''
 
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The entry 6g78 is ON HOLD until Paper Publication
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==RSK4 N-terminal Kinase Domain S232E in complex with AMP-PNP==
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<StructureSection load='6g78' size='340' side='right'caption='[[6g78]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
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Authors: Prischi, F., Ali, M.M.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[6g78]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6G78 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6G78 FirstGlance]. <br>
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Description: RSK4 N-terminal Kinase Domain S232E in complex with AMP-PNP
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6g78 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6g78 OCA], [http://pdbe.org/6g78 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6g78 RCSB], [http://www.ebi.ac.uk/pdbsum/6g78 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6g78 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/KS6A6_HUMAN KS6A6_HUMAN]] Constitutively active serine/threonine-protein kinase that exhibits growth-factor-independent kinase activity and that may participate in p53/TP53-dependent cell growth arrest signaling and play an inhibitory role during embryogenesis.<ref>PMID:15042092</ref> <ref>PMID:15632195</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Non-specific serine/threonine protein kinase]]
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[[Category: Ali, M M]]
[[Category: Prischi, F]]
[[Category: Prischi, F]]
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[[Category: Ali, M.M]]
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[[Category: Agc kinase]]
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[[Category: P90 ribosomal s6 kinase]]
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[[Category: Rsk4]]
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[[Category: Transferase]]

Revision as of 05:55, 17 April 2019

RSK4 N-terminal Kinase Domain S232E in complex with AMP-PNP

PDB ID 6g78

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