This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
6gaj
From Proteopedia
(Difference between revisions)
m (Protected "6gaj" [edit=sysop:move=sysop]) |
|||
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of the T1L reovirus sigma1 coiled coil tail (iodide)== | |
| - | + | <StructureSection load='6gaj' size='340' side='right' caption='[[6gaj]], [[Resolution|resolution]] 1.35Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6gaj]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6GAJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6GAJ FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene></td></tr> | |
| - | [[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6gaj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6gaj OCA], [http://pdbe.org/6gaj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6gaj RCSB], [http://www.ebi.ac.uk/pdbsum/6gaj PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6gaj ProSAT]</span></td></tr> |
| - | [[Category: Dietrich, M | + | </table> |
| - | [[Category: Stehle, | + | == Function == |
| + | [[http://www.uniprot.org/uniprot/SIGM1_REOVL SIGM1_REOVL]] Fiber-like molecule that attaches the virion to the host cell membrane by binding to the primary receptor F11R/JAM-A and to sialic acid containing proteins (coreceptor). The interaction of sigma-1 with F11R is required for NF-kB activation and apoptosis. Binding to both sialic acid and F11R is required to induce maximal levels of apoptosis (By similarity). | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Dietrich, M H]] | ||
| + | [[Category: Stehle, T]] | ||
| + | [[Category: Cell attachment protein]] | ||
| + | [[Category: Coiled coil]] | ||
| + | [[Category: Reovirus sigma1]] | ||
| + | [[Category: Viral protein]] | ||
Revision as of 05:39, 25 April 2018
Crystal structure of the T1L reovirus sigma1 coiled coil tail (iodide)
| |||||||||||
