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4qcb

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==Protein-DNA complex of Vaccinia virus D4 with double-stranded non-specific DNA==
==Protein-DNA complex of Vaccinia virus D4 with double-stranded non-specific DNA==
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<StructureSection load='4qcb' size='340' side='right' caption='[[4qcb]], [[Resolution|resolution]] 2.89&Aring;' scene=''>
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<StructureSection load='4qcb' size='340' side='right'caption='[[4qcb]], [[Resolution|resolution]] 2.89&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4qcb]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Vaccw Vaccw]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QCB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4QCB FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4qcb]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Vaccinia_virus_WR Vaccinia virus WR]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QCB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4QCB FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4dof|4dof]], [[4dog|4dog]], [[4lzb|4lzb]], [[4qc9|4qc9]], [[4qca|4qca]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4qcb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qcb OCA], [https://pdbe.org/4qcb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4qcb RCSB], [https://www.ebi.ac.uk/pdbsum/4qcb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4qcb ProSAT]</span></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">VACWR109, D4R, UNG ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10254 VACCW])</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Uracil-DNA_glycosylase Uracil-DNA glycosylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.2.27 3.2.2.27] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4qcb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qcb OCA], [http://pdbe.org/4qcb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4qcb RCSB], [http://www.ebi.ac.uk/pdbsum/4qcb PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4qcb ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/UNG_VACCW UNG_VACCW]] Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. Also part of a heterodimeric processivity factor which potentiates the DNA polymerase activity. Binds to DNA (By similarity).
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[https://www.uniprot.org/uniprot/UNG_VACCW UNG_VACCW] Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. Also part of a heterodimeric processivity factor which potentiates the DNA polymerase activity. Binds to DNA (By similarity).
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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==See Also==
==See Also==
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*[[DNA glycosylase|DNA glycosylase]]
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*[[DNA glycosylase 3D structures|DNA glycosylase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Uracil-DNA glycosylase]]
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[[Category: Large Structures]]
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[[Category: Vaccw]]
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[[Category: Vaccinia virus WR]]
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[[Category: Banerjee, S]]
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[[Category: Banerjee S]]
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[[Category: Chattopadhyay, D]]
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[[Category: Chattopadhyay D]]
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[[Category: Ricciardi, R]]
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[[Category: Ricciardi R]]
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[[Category: Schormann, N]]
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[[Category: Schormann N]]
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[[Category: A20]]
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[[Category: Component of processivity factor]]
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[[Category: Dna repair enzyme]]
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[[Category: Hydrolase-dna complex]]
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[[Category: Poxvirus]]
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Revision as of 11:23, 15 February 2023

Protein-DNA complex of Vaccinia virus D4 with double-stranded non-specific DNA

PDB ID 4qcb

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