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5eg7

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Current revision (06:25, 5 July 2023) (edit) (undo)
 
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==The cap binding site of influenza virus protein PB2 as a drug target==
==The cap binding site of influenza virus protein PB2 as a drug target==
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<StructureSection load='5eg7' size='340' side='right' caption='[[5eg7]], [[Resolution|resolution]] 1.40&Aring;' scene=''>
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<StructureSection load='5eg7' size='340' side='right'caption='[[5eg7]], [[Resolution|resolution]] 1.40&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5eg7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Influenza_a_virus_(a/swine/quebec/1257777/2010(h3n2)) Influenza a virus (a/swine/quebec/1257777/2010(h3n2))]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5EG7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5EG7 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5eg7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Influenza_A_virus_(A/swine/Quebec/1257777/2010(H3N2)) Influenza A virus (A/swine/Quebec/1257777/2010(H3N2))]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5EG7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5EG7 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MGT:7N-METHYL-8-HYDROGUANOSINE-5-TRIPHOSPHATE'>MGT</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.4&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5eg8|5eg8]], [[5eg9|5eg9]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MGT:7N-METHYL-8-HYDROGUANOSINE-5-TRIPHOSPHATE'>MGT</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PB2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1076704 Influenza A virus (A/swine/Quebec/1257777/2010(H3N2))])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5eg7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5eg7 OCA], [https://pdbe.org/5eg7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5eg7 RCSB], [https://www.ebi.ac.uk/pdbsum/5eg7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5eg7 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5eg7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5eg7 OCA], [http://pdbe.org/5eg7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5eg7 RCSB], [http://www.ebi.ac.uk/pdbsum/5eg7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5eg7 ProSAT]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/G3LZH2_9INFA G3LZH2_9INFA]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Li, K]]
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[[Category: Large Structures]]
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[[Category: Liu, Y]]
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[[Category: Li K]]
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[[Category: Luo, M]]
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[[Category: Liu Y]]
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[[Category: Moura, T Rocha de]]
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[[Category: Luo M]]
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[[Category: Severin, C]]
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[[Category: Rocha de Moura T]]
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[[Category: Zheng, X]]
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[[Category: Severin C]]
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[[Category: Pb2 cap]]
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[[Category: Zheng X]]
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[[Category: Viral protein]]
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Current revision

The cap binding site of influenza virus protein PB2 as a drug target

PDB ID 5eg7

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