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5w35

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Current revision (14:06, 4 October 2023) (edit) (undo)
 
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==Crystal structure of the RNA polymerase domain (RPD) of Mycobacterium tuberculosis primase DnaG in complex with a double-stranded DNA oligomer with a 1-nucleotide overhang==
==Crystal structure of the RNA polymerase domain (RPD) of Mycobacterium tuberculosis primase DnaG in complex with a double-stranded DNA oligomer with a 1-nucleotide overhang==
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<StructureSection load='5w35' size='340' side='right' caption='[[5w35]], [[Resolution|resolution]] 3.31&Aring;' scene=''>
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<StructureSection load='5w35' size='340' side='right'caption='[[5w35]], [[Resolution|resolution]] 3.31&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5w35]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Myctu Myctu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5W35 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5W35 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5w35]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5W35 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5W35 FirstGlance]. <br>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5w33|5w33]], [[5w34|5w34]], [[5w36|5w36]]</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.31&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">dnaG, Rv2343c, MTCY98.12c ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83332 MYCTU])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5w35 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5w35 OCA], [https://pdbe.org/5w35 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5w35 RCSB], [https://www.ebi.ac.uk/pdbsum/5w35 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5w35 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5w35 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5w35 OCA], [http://pdbe.org/5w35 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5w35 RCSB], [http://www.ebi.ac.uk/pdbsum/5w35 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5w35 ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/DNAG_MYCTU DNAG_MYCTU]] RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
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[https://www.uniprot.org/uniprot/DNAG_MYCTU DNAG_MYCTU] RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 5w35" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5w35" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[RNA polymerase 3D structures|RNA polymerase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Myctu]]
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[[Category: Large Structures]]
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[[Category: Hou, C]]
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[[Category: Mycobacterium tuberculosis H37Rv]]
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[[Category: Tsodikov, O V]]
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[[Category: Synthetic construct]]
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[[Category: Dna binding]]
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[[Category: Hou C]]
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[[Category: Dna replication]]
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[[Category: Tsodikov OV]]
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[[Category: Replisome]]
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[[Category: Toprim fold]]
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[[Category: Transferase-dna complex]]
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Current revision

Crystal structure of the RNA polymerase domain (RPD) of Mycobacterium tuberculosis primase DnaG in complex with a double-stranded DNA oligomer with a 1-nucleotide overhang

PDB ID 5w35

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