This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
6d47
From Proteopedia
(Difference between revisions)
m (Protected "6d47" [edit=sysop:move=sysop]) |
|||
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of a DNA polymerase III subunit beta DnaN sliding clamp from Mycobacterium marinum== | |
| - | + | <StructureSection load='6d47' size='340' side='right' caption='[[6d47]], [[Resolution|resolution]] 2.45Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6d47]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6D47 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6D47 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6d47 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6d47 OCA], [http://pdbe.org/6d47 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6d47 RCSB], [http://www.ebi.ac.uk/pdbsum/6d47 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6d47 ProSAT]</span></td></tr> | |
| - | [[ | + | </table> |
| - | [[Category: | + | == Function == |
| + | [[http://www.uniprot.org/uniprot/B2HI47_MYCMM B2HI47_MYCMM]] Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.[PIRNR:PIRNR000804] | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Structural genomic]] | ||
| + | [[Category: Dna binding protein]] | ||
| + | [[Category: Griselimycin]] | ||
| + | [[Category: Mtb]] | ||
| + | [[Category: National institute of allergy and infectious disease]] | ||
| + | [[Category: Niaid]] | ||
| + | [[Category: Ssgcid]] | ||
| + | [[Category: Tuberculosis]] | ||
Revision as of 08:12, 2 May 2018
Crystal structure of a DNA polymerase III subunit beta DnaN sliding clamp from Mycobacterium marinum
| |||||||||||
