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5wpk
From Proteopedia
(Difference between revisions)
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==Structure of the class II 3-hydroxy-3-methylglutaryl-CoA reductase from Streptococcus pneumoniae bound to HMG-CoA and in a partially closed conformation== | ==Structure of the class II 3-hydroxy-3-methylglutaryl-CoA reductase from Streptococcus pneumoniae bound to HMG-CoA and in a partially closed conformation== | ||
| - | <StructureSection load='5wpk' size='340' side='right' caption='[[5wpk]], [[Resolution|resolution]] 2.30Å' scene=''> | + | <StructureSection load='5wpk' size='340' side='right'caption='[[5wpk]], [[Resolution|resolution]] 2.30Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[5wpk]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5WPK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5WPK FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[5wpk]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"diplococcus_pneumoniae"_(klein_1884)_weichselbaum_1886 "diplococcus pneumoniae" (klein 1884) weichselbaum 1886]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5WPK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5WPK FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=HMG:3-HYDROXY-3-METHYLGLUTARYL-COENZYME+A'>HMG</scene>, <scene name='pdbligand=PE4:2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL'>PE4</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=HMG:3-HYDROXY-3-METHYLGLUTARYL-COENZYME+A'>HMG</scene>, <scene name='pdbligand=PE4:2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL'>PE4</scene></td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">mvaA, mvaA_1, mvaA_3, AWW74_09880, ERS019416_00185, ERS019687_00346, ERS020135_00205, ERS020138_01692, ERS020141_01867, ERS020145_01986, ERS020146_01579, ERS020155_00051, ERS020158_01777, ERS020520_02006, ERS020525_01644, ERS020528_00536, ERS020531_01915, ERS020532_00514, ERS020539_01756, ERS020726_02213, ERS020726_02223, ERS020822_01277, ERS021354_03805, ERS021629_07183, ERS021733_05462, ERS232524_02161, ERS367337_00780, ERS409444_00519 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1313 "Diplococcus pneumoniae" (Klein 1884) Weichselbaum 1886])</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Hydroxymethylglutaryl-CoA_reductase_(NADPH) Hydroxymethylglutaryl-CoA reductase (NADPH)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.34 1.1.1.34] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Hydroxymethylglutaryl-CoA_reductase_(NADPH) Hydroxymethylglutaryl-CoA reductase (NADPH)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.34 1.1.1.34] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5wpk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5wpk OCA], [http://pdbe.org/5wpk PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5wpk RCSB], [http://www.ebi.ac.uk/pdbsum/5wpk PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5wpk ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5wpk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5wpk OCA], [http://pdbe.org/5wpk PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5wpk RCSB], [http://www.ebi.ac.uk/pdbsum/5wpk PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5wpk ProSAT]</span></td></tr> | ||
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</div> | </div> | ||
<div class="pdbe-citations 5wpk" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 5wpk" style="background-color:#fffaf0;"></div> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[HMG-CoA Reductase 3D structures|HMG-CoA Reductase 3D structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
[[Category: Kung, Y]] | [[Category: Kung, Y]] | ||
[[Category: Miller, B R]] | [[Category: Miller, B R]] | ||
Revision as of 10:01, 1 January 2020
Structure of the class II 3-hydroxy-3-methylglutaryl-CoA reductase from Streptococcus pneumoniae bound to HMG-CoA and in a partially closed conformation
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