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6cvh
From Proteopedia
(Difference between revisions)
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<StructureSection load='6cvh' size='340' side='right' caption='[[6cvh]], [[Resolution|resolution]] 3.50Å' scene=''> | <StructureSection load='6cvh' size='340' side='right' caption='[[6cvh]], [[Resolution|resolution]] 3.50Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[6cvh]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6CVH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6CVH FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[6cvh]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6CVH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6CVH FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FJG:trans-3-({4-(cyclohexylmethyl)-5-[3-(1-methylcyclopropyl)-5-{[(2R)-1,1,1-trifluoropropan-2-yl]carbamoyl}phenyl]-1,3-thiazole-2-carbonyl}amino)cyclobutane-1-carboxylic+acid'>FJG</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FJG:trans-3-({4-(cyclohexylmethyl)-5-[3-(1-methylcyclopropyl)-5-{[(2R)-1,1,1-trifluoropropan-2-yl]carbamoyl}phenyl]-1,3-thiazole-2-carbonyl}amino)cyclobutane-1-carboxylic+acid'>FJG</scene></td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">RORC, NR1F3, RORG, RZRG ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6cvh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6cvh OCA], [http://pdbe.org/6cvh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6cvh RCSB], [http://www.ebi.ac.uk/pdbsum/6cvh PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6cvh ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6cvh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6cvh OCA], [http://pdbe.org/6cvh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6cvh RCSB], [http://www.ebi.ac.uk/pdbsum/6cvh PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6cvh ProSAT]</span></td></tr> | ||
</table> | </table> | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Human]] | ||
[[Category: Milligan, C]] | [[Category: Milligan, C]] | ||
[[Category: Spurlino, J]] | [[Category: Spurlino, J]] | ||
[[Category: Nuclear protein]] | [[Category: Nuclear protein]] | ||
[[Category: Nuclear receptor rorgt]] | [[Category: Nuclear receptor rorgt]] | ||
Revision as of 08:33, 2 May 2018
Identification and biological evaluation of thiazole-based inverse agonists of RORgt
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