2hhk

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[[Image:2hhk.gif|left|200px]]
[[Image:2hhk.gif|left|200px]]
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{{Structure
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<!--
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|PDB= 2hhk |SIZE=350|CAPTION= <scene name='initialview01'>2hhk</scene>, resolution 2.50&Aring;
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The line below this paragraph, containing "STRUCTURE_2hhk", creates the "Structure Box" on the page.
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|SITE=
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|LIGAND= <scene name='pdbligand=BCL:BACTERIOCHLOROPHYLL+A'>BCL</scene>, <scene name='pdbligand=BPH:BACTERIOPHEOPHYTIN+A'>BPH</scene>, <scene name='pdbligand=CDL:CARDIOLIPIN'>CDL</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=LDA:LAURYL+DIMETHYLAMINE-N-OXIDE'>LDA</scene>, <scene name='pdbligand=PGK:(1R)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL+(9S,10S)-9,10-DIBROMOOCTADECANOATE'>PGK</scene>, <scene name='pdbligand=PGT:(1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL+STEARATE'>PGT</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=U10:UBIQUINONE-10'>U10</scene>
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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|ACTIVITY=
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|GENE=
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|DOMAIN=
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{{STRUCTURE_2hhk| PDB=2hhk | SCENE= }}
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|RELATEDENTRY=[[2hg3|2HG3]], [[2hg9|2HG9]], [[2hh1|2HH1]]
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2hhk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hhk OCA], [http://www.ebi.ac.uk/pdbsum/2hhk PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2hhk RCSB]</span>
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}}
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'''Reaction centre from Rhodobacter sphaeroides strain R-26.1 complexed with dibrominated phosphatidylglycerol'''
'''Reaction centre from Rhodobacter sphaeroides strain R-26.1 complexed with dibrominated phosphatidylglycerol'''
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[[Category: Isaacs, N W.]]
[[Category: Isaacs, N W.]]
[[Category: Roszak, A W.]]
[[Category: Roszak, A W.]]
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[[Category: brominated lipid]]
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[[Category: Brominated lipid]]
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[[Category: lipid binding site]]
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[[Category: Lipid binding site]]
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[[Category: membrane protein]]
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[[Category: Membrane protein]]
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[[Category: photosynthesis]]
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[[Category: Photosynthesis]]
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[[Category: photosynthetic reaction center]]
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[[Category: Photosynthetic reaction center]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May 4 06:18:07 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 03:30:31 2008''
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Revision as of 03:18, 4 May 2008

Image:2hhk.gif

Template:STRUCTURE 2hhk

Reaction centre from Rhodobacter sphaeroides strain R-26.1 complexed with dibrominated phosphatidylglycerol


Overview

This study describes the use of brominated phospholipids to distinguish between lipid and detergent binding sites on the surface of a typical alpha-helical membrane protein. Reaction centers isolated from Rhodobacter sphaeroides were cocrystallized with added brominated phospholipids. X-ray structural analysis of these crystals has revealed the presence of two lipid binding sites from the characteristic strong X-ray scattering from the bromine atoms. These results demonstrate the usefulness of this approach to mapping lipid binding sites at the surface of membrane proteins.

About this Structure

2HHK is a Protein complex structure of sequences from Rhodobacter sphaeroides. Full crystallographic information is available from OCA.

Reference

Brominated lipids identify lipid binding sites on the surface of the reaction center from Rhodobacter sphaeroides., Roszak AW, Gardiner AT, Isaacs NW, Cogdell RJ, Biochemistry. 2007 Mar 20;46(11):2909-16. Epub 2007 Feb 23. PMID:17315985 Page seeded by OCA on Sun May 4 06:18:07 2008

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