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Aldose Reductase

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*<scene name='43/436098/Cv/7'>Active site interactions</scene>. Water molecules are shown as red spheres.
*<scene name='43/436098/Cv/7'>Active site interactions</scene>. Water molecules are shown as red spheres.
*<scene name='43/436098/Cv/9'>Active site tunnel</scene>.
*<scene name='43/436098/Cv/9'>Active site tunnel</scene>.
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== 3D Structures of aldose reductase ==
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[[Aldose reductase 3D structures]]
</StructureSection>
</StructureSection>
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== 3D Structures of Aldose Reductase ==
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== 3D Structures of aldose reductase ==
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
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**[[5jh1]], [[5jgy]] – maAldR – maize<br />
**[[5jh1]], [[5jgy]] – maAldR – maize<br />
**[[5jgw]] – maAldR + NADP<br />
**[[5jgw]] – maAldR + NADP<br />
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**[[5zci]] – DnAldR – ''Debaryomyces nepalensis''<br />
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**[[5zcm]] – DnAldR + NADP<br />
*Aldose Reductase+inhibitors
*Aldose Reductase+inhibitors

Revision as of 10:19, 5 March 2019

Human aldose reductase complex with cofactor NADP (PDB code 1ads)

Drag the structure with the mouse to rotate

3D Structures of aldose reductase

Updated on 05-March-2019

References

  1. ↑ Rondeau JM, Tete-Favier F, Podjarny A, Reymann JM, Barth P, Biellmann JF, Moras D. Novel NADPH-binding domain revealed by the crystal structure of aldose reductase. Nature. 1992 Jan 30;355(6359):469-72. PMID:1734286 doi:http://dx.doi.org/10.1038/355469a0
  2. ↑ Wilson DK, Bohren KM, Gabbay KH, Quiocho FA. An unlikely sugar substrate site in the 1.65 A structure of the human aldose reductase holoenzyme implicated in diabetic complications. Science. 1992 Jul 3;257(5066):81-4. PMID:1621098

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky

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