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1zhm

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==Crystal Structure of the Catalytic Domain of the Coagulation Factor XIa in Complex with Benzamidine (S434A-T475A-K437 Mutant)==
==Crystal Structure of the Catalytic Domain of the Coagulation Factor XIa in Complex with Benzamidine (S434A-T475A-K437 Mutant)==
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<StructureSection load='1zhm' size='340' side='right' caption='[[1zhm]], [[Resolution|resolution]] 1.96&Aring;' scene=''>
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<StructureSection load='1zhm' size='340' side='right'caption='[[1zhm]], [[Resolution|resolution]] 1.96&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1zhm]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZHM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ZHM FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1zhm]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZHM OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=1ZHM FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BEN:BENZAMIDINE'>BEN</scene>, <scene name='pdbligand=GSH:GLUTATHIONE'>GSH</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BEN:BENZAMIDINE'>BEN</scene>, <scene name='pdbligand=GSH:GLUTATHIONE'>GSH</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1zhn|1zhn]], [[1zhp|1zhp]], [[1zhr|1zhr]], [[1zjd|1zjd]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1zhn|1zhn]], [[1zhp|1zhp]], [[1zhr|1zhr]], [[1zjd|1zjd]]</div></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">F11 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">F11 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Coagulation_factor_XIa Coagulation factor XIa], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.27 3.4.21.27] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Coagulation_factor_XIa Coagulation factor XIa], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.27 3.4.21.27] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1zhm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zhm OCA], [http://pdbe.org/1zhm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1zhm RCSB], [http://www.ebi.ac.uk/pdbsum/1zhm PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1zhm ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=1zhm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zhm OCA], [http://pdbe.org/1zhm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1zhm RCSB], [http://www.ebi.ac.uk/pdbsum/1zhm PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1zhm ProSAT]</span></td></tr>
</table>
</table>
== Disease ==
== Disease ==
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</div>
</div>
<div class="pdbe-citations 1zhm" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 1zhm" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Factor XIa|Factor XIa]]
== References ==
== References ==
<references/>
<references/>
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[[Category: Coagulation factor XIa]]
[[Category: Coagulation factor XIa]]
[[Category: Human]]
[[Category: Human]]
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[[Category: Large Structures]]
[[Category: Abdel-Meguid, S S]]
[[Category: Abdel-Meguid, S S]]
[[Category: Babine, R E]]
[[Category: Babine, R E]]

Revision as of 09:04, 20 January 2021

Crystal Structure of the Catalytic Domain of the Coagulation Factor XIa in Complex with Benzamidine (S434A-T475A-K437 Mutant)

PDB ID 1zhm

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