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1zvz

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==Vinculin Head (0-258) in Complex with the Talin Rod Residue 820-844==
==Vinculin Head (0-258) in Complex with the Talin Rod Residue 820-844==
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<StructureSection load='1zvz' size='340' side='right' caption='[[1zvz]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
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<StructureSection load='1zvz' size='340' side='right'caption='[[1zvz]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1zvz]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Chick Chick]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZVZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ZVZ FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1zvz]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Chick Chick]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZVZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ZVZ FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">VCL, VINC1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9031 CHICK])</td></tr>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">VCL, VINC1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9031 CHICK])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1zvz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zvz OCA], [http://pdbe.org/1zvz PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1zvz RCSB], [http://www.ebi.ac.uk/pdbsum/1zvz PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1zvz ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1zvz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zvz OCA], [https://pdbe.org/1zvz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1zvz RCSB], [https://www.ebi.ac.uk/pdbsum/1zvz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1zvz ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/VINC_CHICK VINC_CHICK]] Actin filament (F-actin)-binding protein involved in cell-matrix adhesion and cell-cell adhesion. Regulates cell-surface E-cadherin expression and potentiates mechanosensing by the E-cadherin complex. May also play important roles in cell morphology and locomotion.<ref>PMID:15229287</ref> <ref>PMID:20584916</ref> <ref>PMID:20086044</ref> [[http://www.uniprot.org/uniprot/TLN1_CHICK TLN1_CHICK]] Probably involved in connections of major cytoskeletal structures to the plasma membrane. Talin is a high molecular weight cytoskeletal protein concentrated at regions of cell-substratum contact and, in lymphocytes, at cell-cell contacts.
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[[https://www.uniprot.org/uniprot/VINC_CHICK VINC_CHICK]] Actin filament (F-actin)-binding protein involved in cell-matrix adhesion and cell-cell adhesion. Regulates cell-surface E-cadherin expression and potentiates mechanosensing by the E-cadherin complex. May also play important roles in cell morphology and locomotion.<ref>PMID:15229287</ref> <ref>PMID:20584916</ref> <ref>PMID:20086044</ref> [[https://www.uniprot.org/uniprot/TLN1_CHICK TLN1_CHICK]] Probably involved in connections of major cytoskeletal structures to the plasma membrane. Talin is a high molecular weight cytoskeletal protein concentrated at regions of cell-substratum contact and, in lymphocytes, at cell-cell contacts.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</div>
</div>
<div class="pdbe-citations 1zvz" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 1zvz" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Talin|Talin]]
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*[[Vinculin|Vinculin]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Chick]]
[[Category: Chick]]
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[[Category: Large Structures]]
[[Category: Barsukov, I L]]
[[Category: Barsukov, I L]]
[[Category: Critchley, D R]]
[[Category: Critchley, D R]]

Revision as of 08:18, 27 January 2021

Vinculin Head (0-258) in Complex with the Talin Rod Residue 820-844

PDB ID 1zvz

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