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Antithrombin

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The binding of AT to the heparans or the heparin drug is to a core pentasaccharide. The binding induces conformational change of AT.
The binding of AT to the heparans or the heparin drug is to a core pentasaccharide. The binding induces conformational change of AT.
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==3D structures of antithrombin==
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[[Antithrombin 3D structures]]
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</StructureSection>
</StructureSection>

Revision as of 08:56, 18 March 2019

Glycosylated human antithrombin III complex with heparin (in green) (PDB code 3evj)

Drag the structure with the mouse to rotate

3D structures of antithrombin

Updated on 18-March-2019

References

  1. Li W, Johnson DJ, Esmon CT, Huntington JA. Structure of the antithrombin-thrombin-heparin ternary complex reveals the antithrombotic mechanism of heparin. Nat Struct Mol Biol. 2004 Sep;11(9):857-62. Epub 2004 Aug 15. PMID:15311269 doi:10.1038/nsmb811

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky

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