2an1

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==Structural Genomics, The crystal structure of a putative kinase from Salmonella typhimurim LT2==
==Structural Genomics, The crystal structure of a putative kinase from Salmonella typhimurim LT2==
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<StructureSection load='2an1' size='340' side='right' caption='[[2an1]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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<StructureSection load='2an1' size='340' side='right'caption='[[2an1]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2an1]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Salty Salty]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AN1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2AN1 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2an1]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Salty Salty]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AN1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2AN1 FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">yfjB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=99287 SALTY])</td></tr>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">yfjB ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=99287 SALTY])</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/NAD(+)_kinase NAD(+) kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.23 2.7.1.23] </span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/NAD(+)_kinase NAD(+) kinase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.23 2.7.1.23] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2an1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2an1 OCA], [http://pdbe.org/2an1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2an1 RCSB], [http://www.ebi.ac.uk/pdbsum/2an1 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2an1 ProSAT], [http://www.topsan.org/Proteins/MCSG/2an1 TOPSAN]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2an1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2an1 OCA], [https://pdbe.org/2an1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2an1 RCSB], [https://www.ebi.ac.uk/pdbsum/2an1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2an1 ProSAT], [https://www.topsan.org/Proteins/MCSG/2an1 TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/NADK_SALTY NADK_SALTY]] Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. It can use ATP and other nucleoside triphosphates as a source of phosphorus. NADH can not replace NAD as a substrate.[HAMAP-Rule:MF_00361]<ref>PMID:16682646</ref>
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[[https://www.uniprot.org/uniprot/NADK_SALTY NADK_SALTY]] Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. It can use ATP and other nucleoside triphosphates as a source of phosphorus. NADH can not replace NAD as a substrate.[HAMAP-Rule:MF_00361]<ref>PMID:16682646</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Large Structures]]
[[Category: Salty]]
[[Category: Salty]]
[[Category: Collart, F]]
[[Category: Collart, F]]

Revision as of 08:33, 27 January 2021

Structural Genomics, The crystal structure of a putative kinase from Salmonella typhimurim LT2

PDB ID 2an1

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