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2a1y
From Proteopedia
(Difference between revisions)
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==Crystal Structure of GuaC-GMP complex from Bacillus anthracis at 2.26 A Resolution.== | ==Crystal Structure of GuaC-GMP complex from Bacillus anthracis at 2.26 A Resolution.== | ||
| - | <StructureSection load='2a1y' size='340' side='right' caption='[[2a1y]], [[Resolution|resolution]] 2.27Å' scene=''> | + | <StructureSection load='2a1y' size='340' side='right'caption='[[2a1y]], [[Resolution|resolution]] 2.27Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2a1y]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2a1y]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_cereus_var._anthracis"_(cohn_1872)_smith_et_al._1946 "bacillus cereus var. anthracis" (cohn 1872) smith et al. 1946]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2A1Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2A1Y FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=5GP:GUANOSINE-5-MONOPHOSPHATE'>5GP</scene></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=5GP:GUANOSINE-5-MONOPHOSPHATE'>5GP</scene></td></tr> |
| - | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1ypf|1ypf]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1ypf|1ypf]]</div></td></tr> |
| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">guaC ([ | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">guaC ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1392 "Bacillus cereus var. anthracis" (Cohn 1872) Smith et al. 1946])</td></tr> |
| - | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/GMP_reductase GMP reductase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.7.1.7 1.7.1.7] </span></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2a1y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2a1y OCA], [https://pdbe.org/2a1y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2a1y RCSB], [https://www.ebi.ac.uk/pdbsum/2a1y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2a1y ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/GUAC_BACAN GUAC_BACAN]] Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides (By similarity). |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: GMP reductase]] | [[Category: GMP reductase]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Blagova, E V]] | [[Category: Blagova, E V]] | ||
[[Category: Brannigan, J A]] | [[Category: Brannigan, J A]] | ||
Revision as of 08:24, 27 January 2021
Crystal Structure of GuaC-GMP complex from Bacillus anthracis at 2.26 A Resolution.
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Categories: GMP reductase | Large Structures | Blagova, E V | Brannigan, J A | Fogg, M J | Grenha, R | Levdikov, V M | SPINE, Structural Proteomics in Europe | Wilkinson, A J | Wilson, K S | And nucleotides: nucleotide and nucleoside interconversion | Gmp | Guac | Nucleoside | Oxidoreductase | Purine | Pyrimidine | Spine | Structural genomic | Structural proteomics in europe
