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6b4k
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of human DDX19B(AMPPNP)== | |
| - | + | <StructureSection load='6b4k' size='340' side='right' caption='[[6b4k]], [[Resolution|resolution]] 2.20Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6b4k]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6B4K OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6B4K FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MLI:MALONATE+ION'>MLI</scene></td></tr> | |
| - | [[Category: | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/RNA_helicase RNA helicase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.4.13 3.6.4.13] </span></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6b4k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6b4k OCA], [http://pdbe.org/6b4k PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6b4k RCSB], [http://www.ebi.ac.uk/pdbsum/6b4k PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6b4k ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/DD19B_HUMAN DD19B_HUMAN]] ATP-dependent RNA helicase involved in mRNA export from the nucleus. Rather than unwinding RNA duplexes, DDX19B functions as a remodeler of ribonucleoprotein particles, whereby proteins bound to nuclear mRNA are dissociated and replaced by cytoplasmic mRNA binding proteins. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: RNA helicase]] | ||
| + | [[Category: Cai, S W]] | ||
| + | [[Category: Correia, A R]] | ||
| + | [[Category: Hoelz, A]] | ||
| + | [[Category: Huber, F M]] | ||
| + | [[Category: Jette, C A]] | ||
| + | [[Category: Lin, D H]] | ||
| + | [[Category: Complex]] | ||
| + | [[Category: Dead-box helicase]] | ||
| + | [[Category: Mrna export]] | ||
| + | [[Category: Nuclear pore complex]] | ||
| + | [[Category: Transport protein]] | ||
Revision as of 05:47, 20 June 2018
Crystal structure of human DDX19B(AMPPNP)
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