2idy

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
[[Image:2idy.gif|left|200px]]
[[Image:2idy.gif|left|200px]]
-
{{Structure
+
<!--
-
|PDB= 2idy |SIZE=350|CAPTION= <scene name='initialview01'>2idy</scene>
+
The line below this paragraph, containing "STRUCTURE_2idy", creates the "Structure Box" on the page.
-
|SITE=
+
You may change the PDB parameter (which sets the PDB file loaded into the applet)
-
|LIGAND=
+
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-
|ACTIVITY=
+
or leave the SCENE parameter empty for the default display.
-
|GENE=
+
-->
-
|DOMAIN=
+
{{STRUCTURE_2idy| PDB=2idy | SCENE= }}
-
|RELATEDENTRY=[[2gri|2GRI]]
+
-
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2idy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2idy OCA], [http://www.ebi.ac.uk/pdbsum/2idy PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2idy RCSB]</span>
+
-
}}
+
'''NMR Structure of the SARS-CoV non-structural protein nsp3a'''
'''NMR Structure of the SARS-CoV non-structural protein nsp3a'''
Line 37: Line 34:
[[Category: Subramanian, V.]]
[[Category: Subramanian, V.]]
[[Category: Wuthrich, K.]]
[[Category: Wuthrich, K.]]
-
[[Category: jcsg]]
+
[[Category: Jcsg]]
-
[[Category: joint center for structural genomic]]
+
[[Category: Joint center for structural genomic]]
-
[[Category: protein structure initiative]]
+
[[Category: Protein structure initiative]]
-
[[Category: psi-2]]
+
[[Category: Psi-2]]
-
[[Category: sars coronavirus nmr nsp3a]]
+
[[Category: Sars coronavirus nmr nsp3a]]
-
[[Category: structural genomic]]
+
[[Category: Structural genomic]]
-
[[Category: viral protein]]
+
[[Category: Viral protein]]
-
 
+
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May 4 07:23:19 2008''
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 03:43:00 2008''
+

Revision as of 04:23, 4 May 2008

Template:STRUCTURE 2idy

NMR Structure of the SARS-CoV non-structural protein nsp3a


Overview

This paper describes the structure determination of nsp3a, the N-terminal domain of the severe acute respiratory syndrome coronavirus (SARS-CoV) nonstructural protein 3. nsp3a exhibits a ubiquitin-like globular fold of residues 1 to 112 and a flexibly extended glutamic acid-rich domain of residues 113 to 183. In addition to the four beta-strands and two alpha-helices that are common to ubiquitin-like folds, the globular domain of nsp3a contains two short helices representing a feature that has not previously been observed in these proteins. Nuclear magnetic resonance chemical shift perturbations showed that these unique structural elements are involved in interactions with single-stranded RNA. Structural similarities with proteins involved in various cell-signaling pathways indicate possible roles of nsp3a in viral infection and persistence.

About this Structure

2IDY is a Single protein structure of sequence from Sars coronavirus. Full crystallographic information is available from OCA.

Reference

Nuclear magnetic resonance structure of the N-terminal domain of nonstructural protein 3 from the severe acute respiratory syndrome coronavirus., Serrano P, Johnson MA, Almeida MS, Horst R, Herrmann T, Joseph JS, Neuman BW, Subramanian V, Saikatendu KS, Buchmeier MJ, Stevens RC, Kuhn P, Wuthrich K, J Virol. 2007 Nov;81(21):12049-60. Epub 2007 Aug 29. PMID:17728234 Page seeded by OCA on Sun May 4 07:23:19 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools