2if4
From Proteopedia
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[[Image:2if4.gif|left|200px]] | [[Image:2if4.gif|left|200px]] | ||
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'''Crystal structure of a multi-domain immunophilin from Arabidopsis thaliana''' | '''Crystal structure of a multi-domain immunophilin from Arabidopsis thaliana''' | ||
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[[Category: Granzin, J.]] | [[Category: Granzin, J.]] | ||
[[Category: Weiergraeber, O H.]] | [[Category: Weiergraeber, O H.]] | ||
| - | [[Category: | + | [[Category: Alpha]] |
| - | [[Category: | + | [[Category: Alpha-beta]] |
| - | [[Category: | + | [[Category: Fkbp-like]] |
| - | [[Category: | + | [[Category: Tpr-like]] |
| - | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May 4 07:25:56 2008'' | |
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | |
Revision as of 04:25, 4 May 2008
Crystal structure of a multi-domain immunophilin from Arabidopsis thaliana
Overview
FKBP42 is a membrane-anchored immunophilin playing a critical role in morphogenesis and development of higher plants. We present the X-ray structure of the cytoplasmic portion of FKBP42 comprising both the FKBP-like domain and the TPR domain at 2.85 A resolution. The data shed light on the probable binding modes of key interaction partners, including HSP90 and two classes of ABC transporters. The resulting models provide a structural background for further investigation of the unique biological properties of this protein.
About this Structure
2IF4 is a Single protein structure of sequence from Arabidopsis thaliana. Full crystallographic information is available from OCA.
Reference
Crystal structure of a multi-domain immunophilin from Arabidopsis thaliana: a paradigm for regulation of plant ABC transporters., Granzin J, Eckhoff A, Weiergraber OH, J Mol Biol. 2006 Dec 8;364(4):799-809. Epub 2006 Sep 26. PMID:17045295 Page seeded by OCA on Sun May 4 07:25:56 2008
