2cqh
From Proteopedia
(Difference between revisions)
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==Solution structure of the RNA binding domain of IGF-II mRNA-binding protein 2== | ==Solution structure of the RNA binding domain of IGF-II mRNA-binding protein 2== | ||
| - | <StructureSection load='2cqh' size='340' side='right' caption='[[2cqh]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | + | <StructureSection load='2cqh' size='340' side='right'caption='[[2cqh]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2cqh]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2cqh]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CQH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CQH FirstGlance]. <br> |
| - | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Imp2 ([ | + | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Imp2 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2cqh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cqh OCA], [https://pdbe.org/2cqh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2cqh RCSB], [https://www.ebi.ac.uk/pdbsum/2cqh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2cqh ProSAT], [https://www.topsan.org/Proteins/RSGI/2cqh TOPSAN]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/IF2B2_HUMAN IF2B2_HUMAN]] Binds to the 5'-UTR of the insulin-like growth factor 2 (IGF2) mRNAs. Binding is isoform-specific. May regulate translation of target mRNAs.<ref>PMID:9891060</ref> |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2cqh ConSurf]. | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2cqh ConSurf]. | ||
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Insulin-like growth factor 2 mRNA-binding protein|Insulin-like growth factor 2 mRNA-binding protein]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Human]] | [[Category: Human]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Inoue, M]] | [[Category: Inoue, M]] | ||
[[Category: Kigawa, T]] | [[Category: Kigawa, T]] | ||
Revision as of 11:46, 3 February 2021
Solution structure of the RNA binding domain of IGF-II mRNA-binding protein 2
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Categories: Human | Large Structures | Inoue, M | Kigawa, T | Muto, Y | Structural genomic | Shirouzu, M | Suzuki, S | Terada, T | Yokoyama, S | National project on protein structural and functional analyse | Nppsfa | Rbd | Rna binding domain | Rna binding protein | Rna recognition motif | Rnp | Rrm | Rsgi
