This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
2ctm
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
==Solution structure of the 14th KH type I domain from human Vigilin== | ==Solution structure of the 14th KH type I domain from human Vigilin== | ||
| - | <StructureSection load='2ctm' size='340' side='right' caption='[[2ctm]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | + | <StructureSection load='2ctm' size='340' side='right'caption='[[2ctm]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2ctm]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2ctm]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CTM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CTM FirstGlance]. <br> |
| - | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">HDLBP ([ | + | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">HDLBP ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ctm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ctm OCA], [https://pdbe.org/2ctm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ctm RCSB], [https://www.ebi.ac.uk/pdbsum/2ctm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ctm ProSAT], [https://www.topsan.org/Proteins/RSGI/2ctm TOPSAN]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/VIGLN_HUMAN VIGLN_HUMAN]] Appears to play a role in cell sterol metabolism. It may function to protect cells from over-accumulation of cholesterol. |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
| Line 22: | Line 22: | ||
</StructureSection> | </StructureSection> | ||
[[Category: Human]] | [[Category: Human]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Inoue, M]] | [[Category: Inoue, M]] | ||
[[Category: Kigawa, T]] | [[Category: Kigawa, T]] | ||
Revision as of 11:50, 3 February 2021
Solution structure of the 14th KH type I domain from human Vigilin
| |||||||||||
Categories: Human | Large Structures | Inoue, M | Kigawa, T | Koshiba, S | Structural genomic | Tomizawa, T | Yokoyama, S | Beta-alpha-alpha-beta-beta-alpha structure | Cell sterol metabolism | K homology type i domain | National project on protein structural and functional analyse | Nppsfa | Rna binding protein | Rna-binding | Rsgi | Transport protein
