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User:Ricardo Alberto Chiong Zevallos/Sandbox 1
From Proteopedia
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You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue. | You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue. | ||
| - | Urgente: nesse link eu coloquei os artigos para procurar os detalhes estruturais, ainda não entendi como pegar a estrutura isolada da BMI1 (sem as outras que formam o complexo PRC1) e mostrar no pymol: https://drive.google.com/drive/folders/1l195aNuY6joOd74GKKxa-XWTRMBv_uWF?usp=sharing | + | '''Urgente: nesse link eu coloquei os artigos para procurar os detalhes estruturais, ainda não entendi como pegar a estrutura isolada da BMI1 (sem as outras que formam o complexo PRC1) e mostrar no pymol: https://drive.google.com/drive/folders/1l195aNuY6joOd74GKKxa-XWTRMBv_uWF?usp=sharing |
pode apagar esse recado depois que você ler, vou deixar o link nas referências | pode apagar esse recado depois que você ler, vou deixar o link nas referências | ||
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== Function == | == Function == | ||
BMI1 is a ring finger protein that is component of a Polycomb group (PcG) multiprotein PRC1-like complex, which epigenetically repress regulatory genes, such as Hox genes, related to embryonic development and self-renewal of somatic stem-cells. BMI1 is central in the DNA damage repair, being the aberrant expression associated with numerous cancers and resistance to some types of chemotherapies. | BMI1 is a ring finger protein that is component of a Polycomb group (PcG) multiprotein PRC1-like complex, which epigenetically repress regulatory genes, such as Hox genes, related to embryonic development and self-renewal of somatic stem-cells. BMI1 is central in the DNA damage repair, being the aberrant expression associated with numerous cancers and resistance to some types of chemotherapies. | ||
Revision as of 23:48, 27 May 2018
Your Heading Here (maybe something like 'Structure')
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References
- ↑ Hanson, R. M., Prilusky, J., Renjian, Z., Nakane, T. and Sussman, J. L. (2013), JSmol and the Next-Generation Web-Based Representation of 3D Molecular Structure as Applied to Proteopedia. Isr. J. Chem., 53:207-216. doi:http://dx.doi.org/10.1002/ijch.201300024
- ↑ Herraez A. Biomolecules in the computer: Jmol to the rescue. Biochem Mol Biol Educ. 2006 Jul;34(4):255-61. doi: 10.1002/bmb.2006.494034042644. PMID:21638687 doi:10.1002/bmb.2006.494034042644
[| BMI1 in NCBI] [| BMI1 in NCBI] [| BMI1 in NCBI]
https://drive.google.com/drive/folders/1l195aNuY6joOd74GKKxa-XWTRMBv_uWF?usp=sharing
