5zo2
From Proteopedia
(Difference between revisions)
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- | '''Unreleased structure''' | ||
- | + | ==Crystal structure of mouse nectin-like molecule 4 (mNecl-4) full ectodomain in complex with mouse nectin-like molecule 1 (mNecl-1) Ig1 domain, 3.3A== | |
- | + | <StructureSection load='5zo2' size='340' side='right' caption='[[5zo2]], [[Resolution|resolution]] 3.29Å' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[5zo2]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ZO2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ZO2 FirstGlance]. <br> | |
- | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr> | |
- | [[Category: | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1z9m|1z9m]], [[5zo1|5zo1]]</td></tr> |
+ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5zo2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5zo2 OCA], [http://pdbe.org/5zo2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5zo2 RCSB], [http://www.ebi.ac.uk/pdbsum/5zo2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5zo2 ProSAT]</span></td></tr> | ||
+ | </table> | ||
+ | == Function == | ||
+ | [[http://www.uniprot.org/uniprot/CADM4_MOUSE CADM4_MOUSE]] Involved in the cell-cell adhesion. Has calcium- and magnesium-independent cell-cell adhesion activity. May have tumor-suppressor activity.<ref>PMID:14659875</ref> [[http://www.uniprot.org/uniprot/CADM3_MOUSE CADM3_MOUSE]] Involved in the cell-cell adhesion. Has both calcium-independent homophilic cell-cell adhesion activity and calcium-independent heterophilic cell-cell adhesion activity with IGSF4, NECTIN1 and NECTIN3. Interaction with EPB41L1 may regulate structure or function of cell-cell junctions.<ref>PMID:15741237</ref> <ref>PMID:15893517</ref> | ||
+ | == References == | ||
+ | <references/> | ||
+ | __TOC__ | ||
+ | </StructureSection> | ||
+ | [[Category: An, T]] | ||
+ | [[Category: Cui, S]] | ||
+ | [[Category: Fan, Z]] | ||
+ | [[Category: Hu, G]] | ||
+ | [[Category: Ju, W]] | ||
+ | [[Category: Li, C]] | ||
+ | [[Category: Li, D]] | ||
+ | [[Category: Li, J]] | ||
+ | [[Category: Liu, X]] | ||
+ | [[Category: Peng, X]] | ||
+ | [[Category: Qiang, B]] | ||
+ | [[Category: Qin, B]] | ||
+ | [[Category: Shu, P]] | ||
+ | [[Category: Wang, M]] | ||
+ | [[Category: Wojdyla, J A]] | ||
+ | [[Category: Xiang, P]] | ||
+ | [[Category: Yin, B]] | ||
+ | [[Category: Yuan, J]] | ||
+ | [[Category: Axon]] | ||
+ | [[Category: Cadm]] | ||
+ | [[Category: Cell adhesion]] | ||
+ | [[Category: Cell adhesion molecule]] | ||
+ | [[Category: Glycoprotein]] | ||
+ | [[Category: Heterogeneous dimer]] | ||
+ | [[Category: Ig domain]] | ||
+ | [[Category: Molecular replacement]] | ||
+ | [[Category: Myelogenesis]] | ||
+ | [[Category: Necl-1]] | ||
+ | [[Category: Necl-4]] | ||
+ | [[Category: Nectin-like]] | ||
+ | [[Category: Schwann cell]] | ||
+ | [[Category: Syncam]] |
Revision as of 08:10, 30 January 2019
Crystal structure of mouse nectin-like molecule 4 (mNecl-4) full ectodomain in complex with mouse nectin-like molecule 1 (mNecl-1) Ig1 domain, 3.3A
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Categories: An, T | Cui, S | Fan, Z | Hu, G | Ju, W | Li, C | Li, D | Li, J | Liu, X | Peng, X | Qiang, B | Qin, B | Shu, P | Wang, M | Wojdyla, J A | Xiang, P | Yin, B | Yuan, J | Axon | Cadm | Cell adhesion | Cell adhesion molecule | Glycoprotein | Heterogeneous dimer | Ig domain | Molecular replacement | Myelogenesis | Necl-1 | Necl-4 | Nectin-like | Schwann cell | Syncam