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2dl9

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==Solution structure of the Ig-like domain of human Leucine-rich repeat-containing protein 4==
==Solution structure of the Ig-like domain of human Leucine-rich repeat-containing protein 4==
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<StructureSection load='2dl9' size='340' side='right' caption='[[2dl9]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
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<StructureSection load='2dl9' size='340' side='right'caption='[[2dl9]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2dl9]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DL9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2DL9 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2dl9]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DL9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DL9 FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">LRRC4, BAG, UNQ554/PRO1111 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">LRRC4, BAG, UNQ554/PRO1111 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2dl9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dl9 OCA], [http://pdbe.org/2dl9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2dl9 RCSB], [http://www.ebi.ac.uk/pdbsum/2dl9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2dl9 ProSAT], [http://www.topsan.org/Proteins/RSGI/2dl9 TOPSAN]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dl9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dl9 OCA], [https://pdbe.org/2dl9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dl9 RCSB], [https://www.ebi.ac.uk/pdbsum/2dl9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dl9 ProSAT], [https://www.topsan.org/Proteins/RSGI/2dl9 TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/LRRC4_HUMAN LRRC4_HUMAN]] Synaptic adhesion protein. Regulates the formation of exitatory synapses through the recruitment of pre-and-postsynaptic proteins. Organize the lamina/pathway-specific differentiation of dendrites. Plays a important role for auditory synaptic responses. Involved in the suppression of glioma (By similarity).
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[[https://www.uniprot.org/uniprot/LRRC4_HUMAN LRRC4_HUMAN]] Synaptic adhesion protein. Regulates the formation of exitatory synapses through the recruitment of pre-and-postsynaptic proteins. Organize the lamina/pathway-specific differentiation of dendrites. Plays a important role for auditory synaptic responses. Involved in the suppression of glioma (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Human]]
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[[Category: Large Structures]]
[[Category: Hayashi, F]]
[[Category: Hayashi, F]]
[[Category: Nagashima, T]]
[[Category: Nagashima, T]]

Revision as of 12:06, 3 February 2021

Solution structure of the Ig-like domain of human Leucine-rich repeat-containing protein 4

PDB ID 2dl9

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