2do4
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
==Solution structure of the RNA binding domain of squamous cell carcinoma antigen recognized by T cells 3== | ==Solution structure of the RNA binding domain of squamous cell carcinoma antigen recognized by T cells 3== | ||
| - | <StructureSection load='2do4' size='340' side='right' caption='[[2do4]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | + | <StructureSection load='2do4' size='340' side='right'caption='[[2do4]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2do4]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2do4]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DO4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DO4 FirstGlance]. <br> |
| - | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">SART3 ([ | + | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">SART3 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2do4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2do4 OCA], [https://pdbe.org/2do4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2do4 RCSB], [https://www.ebi.ac.uk/pdbsum/2do4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2do4 ProSAT], [https://www.topsan.org/Proteins/RSGI/2do4 TOPSAN]</span></td></tr> |
</table> | </table> | ||
== Disease == | == Disease == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/SART3_HUMAN SART3_HUMAN]] Defects in SART3 are the cause of disseminated superficial actinic porokeratosis type 1 (DSAP1) [MIM:[https://omim.org/entry/175900 175900]]. DSAP1 is an autosomal dominant disorder, characterized by multiple superficial keratotic lesions surrounded by a slightly raised keratotic border, developing during the third or fourth decade of life on sun-exposed areas of skin.<ref>PMID:15840095</ref> |
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/SART3_HUMAN SART3_HUMAN]] Regulates Tat transactivation activity through direct interaction. May be a cellular factor for HIV-1 gene expression and viral replication.<ref>PMID:11959860</ref> |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
| Line 26: | Line 26: | ||
</StructureSection> | </StructureSection> | ||
[[Category: Human]] | [[Category: Human]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Inoue, M]] | [[Category: Inoue, M]] | ||
[[Category: Kigawa, T]] | [[Category: Kigawa, T]] | ||
Revision as of 11:32, 10 February 2021
Solution structure of the RNA binding domain of squamous cell carcinoma antigen recognized by T cells 3
| |||||||||||
