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2dn7
From Proteopedia
(Difference between revisions)
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==Solution structures of the 6th fn3 domain of human receptor-type tyrosine-protein phosphatase F== | ==Solution structures of the 6th fn3 domain of human receptor-type tyrosine-protein phosphatase F== | ||
| - | <StructureSection load='2dn7' size='340' side='right' caption='[[2dn7]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | + | <StructureSection load='2dn7' size='340' side='right'caption='[[2dn7]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2dn7]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2dn7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DN7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DN7 FirstGlance]. <br> |
| - | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PTPRF, LAR ([ | + | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PTPRF, LAR ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> |
| - | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Protein-tyrosine-phosphatase Protein-tyrosine-phosphatase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.48 3.1.3.48] </span></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dn7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dn7 OCA], [https://pdbe.org/2dn7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dn7 RCSB], [https://www.ebi.ac.uk/pdbsum/2dn7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dn7 ProSAT], [https://www.topsan.org/Proteins/RSGI/2dn7 TOPSAN]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/PTPRF_HUMAN PTPRF_HUMAN]] Possible cell adhesion receptor. It possesses an intrinsic protein tyrosine phosphatase activity (PTPase).<ref>PMID:10338209</ref> The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one.<ref>PMID:10338209</ref> |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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==See Also== | ==See Also== | ||
| - | *[[Tyrosine phosphatase|Tyrosine phosphatase]] | + | *[[Tyrosine phosphatase 3D structures|Tyrosine phosphatase 3D structures]] |
== References == | == References == | ||
<references/> | <references/> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Human]] | [[Category: Human]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Protein-tyrosine-phosphatase]] | [[Category: Protein-tyrosine-phosphatase]] | ||
[[Category: Inoue, M]] | [[Category: Inoue, M]] | ||
Revision as of 11:30, 10 February 2021
Solution structures of the 6th fn3 domain of human receptor-type tyrosine-protein phosphatase F
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Categories: Human | Large Structures | Protein-tyrosine-phosphatase | Inoue, M | Kigawa, T | Koshiba, S | Structural genomic | Sato, M | Tochio, N | Yokoyama, S | Hydrolase | Lar protein | Leukocyte antigen related | National project on protein structural and functional analyse | Nppsfa | Rsgi | Signaling protein
