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== Function == | == Function == | ||
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| + | The binding of CIC to ATXN1 AXH domain leads to the formation and stabilization of ATXN1 oligomers, which are postulated to be the precursors of the disease. | ||
== Disease == | == Disease == | ||
Revision as of 06:42, 5 June 2018
Protein-protein interaction between Ataxin-1 and Capicua
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References
- ↑ Kim E, Lu HC, Zoghbi HY, Song JJ. Structural basis of protein complex formation and reconfiguration by polyglutamine disease protein Ataxin-1 and Capicua. Genes Dev. 2013 Mar 15;27(6):590-5. doi: 10.1101/gad.212068.112. PMID:23512657 doi:http://dx.doi.org/10.1101/gad.212068.112
