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5ztj
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal Structure of GyraseA C-Terminal Domain from Salmonella typhi at 2.4A Resolution== | |
| - | + | <StructureSection load='5ztj' size='340' side='right'caption='[[5ztj]], [[Resolution|resolution]] 2.40Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5ztj]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_typhi"_schroeter_1886 "bacillus typhi" schroeter 1886]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ZTJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ZTJ FirstGlance]. <br> | |
| - | + | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">gyrA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=90370 "Bacillus typhi" Schroeter 1886])</td></tr> | |
| - | [[Category: | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA_topoisomerase_(ATP-hydrolyzing) DNA topoisomerase (ATP-hydrolyzing)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.99.1.3 5.99.1.3] </span></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ztj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ztj OCA], [http://pdbe.org/5ztj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ztj RCSB], [http://www.ebi.ac.uk/pdbsum/5ztj PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ztj ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/A0A1U7FVV6_SALET A0A1U7FVV6_SALET]] A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.[HAMAP-Rule:MF_01897] | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Bacillus typhi schroeter 1886]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Ethayathulla, A S]] | ||
| + | [[Category: Gupta, D]] | ||
| + | [[Category: Kaur, G]] | ||
| + | [[Category: Kaur, P]] | ||
| + | [[Category: Sachdeva, E]] | ||
[[Category: Sharma, S]] | [[Category: Sharma, S]] | ||
| - | + | [[Category: Singh, T P]] | |
| - | + | ||
| - | [[Category: Singh, T | + | |
[[Category: Tiwari, P]] | [[Category: Tiwari, P]] | ||
| - | [[Category: | + | [[Category: Beta propeller]] |
| - | [[Category: | + | [[Category: Dna binding protein]] |
| - | [[Category: | + | [[Category: Gyr-ctd]] |
| + | [[Category: Topoisomerase]] | ||
Revision as of 07:19, 21 May 2019
Crystal Structure of GyraseA C-Terminal Domain from Salmonella typhi at 2.4A Resolution
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