6go6
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==TdT chimera (Loop1 of pol mu) - ternary complex with downstream dsDNA== | |
| - | + | <StructureSection load='6go6' size='340' side='right'caption='[[6go6]], [[Resolution|resolution]] 2.09Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6go6]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6GO6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6GO6 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DCT:2,3-DIDEOXYCYTIDINE+5-TRIPHOSPHATE'>DCT</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6go6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6go6 OCA], [http://pdbe.org/6go6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6go6 RCSB], [http://www.ebi.ac.uk/pdbsum/6go6 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6go6 ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/TDT_MOUSE TDT_MOUSE]] Template-independent DNA polymerase which catalyzes the random addition of deoxynucleoside 5'-triphosphate to the 3'-end of a DNA initiator. One of the in vivo functions of this enzyme is the addition of nucleotides at the junction (N region) of rearranged Ig heavy chain and T-cell receptor gene segments during the maturation of B- and T-cells. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Delarue, M]] | ||
| + | [[Category: Gerodimos, C A]] | ||
| + | [[Category: Lieber, M R]] | ||
[[Category: Rosario, S]] | [[Category: Rosario, S]] | ||
| - | [[Category: | + | [[Category: H, J Loc]] |
| - | [[Category: | + | [[Category: Dna binding protein]] |
| - | [[Category: | + | [[Category: Dna bridging]] |
| - | [[Category: | + | [[Category: Dna polymerase polx]] |
| + | [[Category: Nhej pathway]] | ||
Revision as of 22:44, 5 June 2019
TdT chimera (Loop1 of pol mu) - ternary complex with downstream dsDNA
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