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5npq
From Proteopedia
(Difference between revisions)
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==Human N-myristoyltransferase 1 (MNT1) with Myristoyl-CoA analogue X10 bound== | ==Human N-myristoyltransferase 1 (MNT1) with Myristoyl-CoA analogue X10 bound== | ||
| - | <StructureSection load='5npq' size='340' side='right' caption='[[5npq]], [[Resolution|resolution]] 2.37Å' scene=''> | + | <StructureSection load='5npq' size='340' side='right'caption='[[5npq]], [[Resolution|resolution]] 2.37Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[5npq]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[5npq]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5NPQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5NPQ FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=94Q:~{S}-[2-[3-[[(2~{S})-4-[[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-4-oxidanyl-3-phosphonooxy-oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxy-3,3-dimethyl-2-oxidanyl-butanoyl]amino]propanoylamino]ethyl]+9-(3-but-3-ynyl-1,2-diazirin-3-yl)nonanethioate'>94Q</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.372Å</td></tr> |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=94Q:~{S}-[2-[3-[[(2~{S})-4-[[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-4-oxidanyl-3-phosphonooxy-oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxy-3,3-dimethyl-2-oxidanyl-butanoyl]amino]propanoylamino]ethyl]+9-(3-but-3-ynyl-1,2-diazirin-3-yl)nonanethioate'>94Q</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5npq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5npq OCA], [https://pdbe.org/5npq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5npq RCSB], [https://www.ebi.ac.uk/pdbsum/5npq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5npq ProSAT]</span></td></tr> | |
| - | + | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/NMT1_HUMAN NMT1_HUMAN] Adds a myristoyl group to the N-terminal glycine residue of certain cellular and viral proteins. |
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Homo sapiens]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: Fedoryshchak | + | [[Category: Fedoryshchak R]] |
| - | [[Category: Perez-Dorado | + | [[Category: Perez-Dorado I]] |
| - | [[Category: Shen | + | [[Category: Shen M]] |
| - | [[Category: Tate | + | [[Category: Tate EW]] |
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Current revision
Human N-myristoyltransferase 1 (MNT1) with Myristoyl-CoA analogue X10 bound
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