2j1a

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
[[Image:2j1a.gif|left|200px]]
[[Image:2j1a.gif|left|200px]]
-
{{Structure
+
<!--
-
|PDB= 2j1a |SIZE=350|CAPTION= <scene name='initialview01'>2j1a</scene>, resolution 1.49&Aring;
+
The line below this paragraph, containing "STRUCTURE_2j1a", creates the "Structure Box" on the page.
-
|SITE= <scene name='pdbsite=AC1:Ca+Binding+Site+For+Chain+A'>AC1</scene>
+
You may change the PDB parameter (which sets the PDB file loaded into the applet)
-
|LIGAND= <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene>
+
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-
|ACTIVITY=
+
or leave the SCENE parameter empty for the default display.
-
|GENE=
+
-->
-
|DOMAIN=
+
{{STRUCTURE_2j1a| PDB=2j1a | SCENE= }}
-
|RELATEDENTRY=
+
-
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2j1a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2j1a OCA], [http://www.ebi.ac.uk/pdbsum/2j1a PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2j1a RCSB]</span>
+
-
}}
+
'''STRUCTURE OF CBM32 FROM CLOSTRIDIUM PERFRINGENS BETA-N-ACETYLHEXOSAMINIDASE GH84C IN COMPLEX WITH GALACTOSE'''
'''STRUCTURE OF CBM32 FROM CLOSTRIDIUM PERFRINGENS BETA-N-ACETYLHEXOSAMINIDASE GH84C IN COMPLEX WITH GALACTOSE'''
Line 27: Line 24:
[[Category: Boraston, A B.]]
[[Category: Boraston, A B.]]
[[Category: Ficko-Blean, E.]]
[[Category: Ficko-Blean, E.]]
-
[[Category: gh84c]]
+
[[Category: Gh84c]]
-
[[Category: glycoside hydrolase,cbm32]]
+
[[Category: Glycoside hydrolase,cbm32]]
-
[[Category: hydrolase]]
+
[[Category: Hydrolase]]
-
[[Category: protein-carbohydrate interaction]]
+
[[Category: Protein-carbohydrate interaction]]
-
 
+
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May 4 08:12:27 2008''
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 03:51:42 2008''
+

Revision as of 05:12, 4 May 2008

Image:2j1a.gif

Template:STRUCTURE 2j1a

STRUCTURE OF CBM32 FROM CLOSTRIDIUM PERFRINGENS BETA-N-ACETYLHEXOSAMINIDASE GH84C IN COMPLEX WITH GALACTOSE


Overview

Clostridium perfringens is a notable colonizer of the human gastrointestinal tract. This bacterium is quite remarkable for a human pathogen by the number of glycoside hydrolases found in its genome. The modularity of these enzymes is striking as is the frequent occurrence of modules having amino acid sequence identity with family 32 carbohydrate-binding modules (CBMs), often referred to as F5/8 domains. Here we report the properties of family 32 CBMs from a C. perfringens N-acetyl-beta-hexosaminidase. Macroarray, UV difference, and isothermal titration calorimetry binding studies indicate a preference for the disaccharide LacNAc (beta-d-galactosyl-1,4-beta-d-N-acetylglucosamine). The molecular details of the interaction of this CBM with galactose, LacNAc, and the type II blood group H-trisaccharide are revealed by x-ray crystallographic studies at resolutions of 1.49, 2.4, and 2.3 A, respectively.

About this Structure

2J1A is a Single protein structure of sequence from Clostridium perfringens. Full crystallographic information is available from OCA.

Reference

The interaction of a carbohydrate-binding module from a Clostridium perfringens N-acetyl-beta-hexosaminidase with its carbohydrate receptor., Ficko-Blean E, Boraston AB, J Biol Chem. 2006 Dec 8;281(49):37748-57. Epub 2006 Sep 21. PMID:16990278 Page seeded by OCA on Sun May 4 08:12:27 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2j1a"
Personal tools