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2dul

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==Crystal structure of tRNA G26 methyltransferase Trm1 in apo form from Pyrococcus horikoshii==
==Crystal structure of tRNA G26 methyltransferase Trm1 in apo form from Pyrococcus horikoshii==
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<StructureSection load='2dul' size='340' side='right' caption='[[2dul]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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<StructureSection load='2dul' size='340' side='right'caption='[[2dul]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2dul]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/'pyrococcus_shinkaii' 'pyrococcus shinkaii']. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DUL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2DUL FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2dul]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/'pyrococcus_shinkaii' 'pyrococcus shinkaii']. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DUL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DUL FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">trm1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=53953 'Pyrococcus shinkaii'])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">trm1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=53953 'Pyrococcus shinkaii'])</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Transferase Transferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.213, 2.1.1.214, 2.1.1.215 and 2.1.1.216 2.1.1.213, 2.1.1.214, 2.1.1.215 and 2.1.1.216] </span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Transferase Transferase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.213, 2.1.1.214, 2.1.1.215 and 2.1.1.216 2.1.1.213, 2.1.1.214, 2.1.1.215 and 2.1.1.216] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2dul FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dul OCA], [http://pdbe.org/2dul PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2dul RCSB], [http://www.ebi.ac.uk/pdbsum/2dul PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2dul ProSAT], [http://www.topsan.org/Proteins/RSGI/2dul TOPSAN]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dul FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dul OCA], [https://pdbe.org/2dul PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dul RCSB], [https://www.ebi.ac.uk/pdbsum/2dul PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dul ProSAT], [https://www.topsan.org/Proteins/RSGI/2dul TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/TRM1_PYRHO TRM1_PYRHO]] Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups (By similarity).
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[[https://www.uniprot.org/uniprot/TRM1_PYRHO TRM1_PYRHO]] Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Pyrococcus shinkaii]]
[[Category: Pyrococcus shinkaii]]
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[[Category: Large Structures]]
[[Category: Transferase]]
[[Category: Transferase]]
[[Category: Bessho, Y]]
[[Category: Bessho, Y]]

Revision as of 11:37, 10 February 2021

Crystal structure of tRNA G26 methyltransferase Trm1 in apo form from Pyrococcus horikoshii

PDB ID 2dul

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