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Gp41

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*Gp41 from HIV-1
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*Gp41 from HIV-1; Domains – core 509-661; N-peptide 541-590; transmembrane 670-709; tail 750-854
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**[[1aik]], [[1df4]], [[1df5]], [[1qr8]], [[1qr9]], [[1dlb]], [[1jpx]] – Gp41 thermostable core domain residues 544-579, 623-656<br />
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**[[2zfc]], [[3u91]] – Gp41 N-terminal residues 1-49 <br />
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**[[1env]], [[3cp1]], [[3cyo]], [[1f23]], [[1k33]], [[1k34]], [[1i5x]], [[1i5y]], [[2ot5]], [[5ka6]], [[5ka5]] – Gp41 thermostable core domain (mutant)<br />
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**[[3k9a]] – Gp41 residues 1-108 (mutant)<br />
**[[3k9a]] – Gp41 residues 1-108 (mutant)<br />
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**[[1szt]] – Gp41 thermostable domain residues 541-574<br />
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**[[1aik]], [[1df4]], [[1df5]], [[1qr8]], [[1qr9]], [[1dlb]], [[1jpx]], [[1szt]], [[3vu5]], [[3vu6]] - Gp41 N-peptide domain <br />
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**[[6b3u]] – Gp41 transmembrane domain residues 670-709 - NMR<br />
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**[[1env]], [[3cp1]], [[3cyo]], [[1f23]], [[1k33]], [[1k34]], [[1i5x]], [[1i5y]], [[2ot5]], [[5ka6]], [[5ka5]], [[4i2l]] – Gp41 N-peptide domain (mutant)<br />
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**[[5vwl]] – Gp41 tail residues 750-854 - NMR<br />
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**[[2z2t]], [[2zzo]], [[3aha]], [[3vie]], [[2r3c]], [[2r5b]], [[2r5d]], [[3l36]], [[3l37]], [[3vgy]], [[3vh7]], [[3vtp]], [[5h0n]] – Gp41 N-peptide domain + fusion inhibitor peptide<br />
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**[[2z2t]], [[2zzo]], [[3aha]], [[3vie]], [[2r3c]], [[2r5b]], [[2r5d]], [[3l36]], [[3l37]], [[3vgy]], [[3vh7]], [[3vtp]], [[3vu5]], [[3vu6]], [[5h0n]] – Gp41 N-heptad repeat + Gp41 fusion inhibitor peptide<br />
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**[[6b3u]] – Gp41 transmembrane domain - NMR<br />
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**[[2zfc]] – Gp41 N-terminal residues 1-49 <br />
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**[[5vwl]] – Gp41 tail domain - NMR<br />
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**[[3u91]] – Gp41 N-terminal residues 7-39<br />
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**[[5v8l]], [[5v8m]], [[5uty]], [[5utf]], [[5um8]], [[5jsa]], [[5js9]], [[5i8h]], [[5d9q]], [[5cjx]], [[5c7k]], [[6ck9]], [[6chb]], [[6ch9]], [[6ch8]], [[6ch7]], [[5w6d]], [[4nrx]], [[5fyk]], [[5fyj]], [[4nco]] – Gp41 core + Gp120 + antibody<br />
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**[[4hlr]] – Gp41 N-terminal (mutant) <br />
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**[[6cdi]] – Gp41 core + Gp120 + antibody – Cryo EM<br />
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**[[4i2l]] – Gp41 N-peptide residues 549-589 (mutant)<br />
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**[[5u1f]], [[5thr]] – Gp41 core + Gp120 + antibody + CD4<br />
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**[[5v8l]], [[5v8m]], [[5uty]], [[5utf]], [[5um8]], [[5jsa]], [[5js9]], [[5i8h]], [[5d9q]], [[5cjx]], [[5c7k]], [[6ck9]], [[6chb]], [[6ch9]], [[6ch8]], [[6ch7]], [[5w6d]], [[4nrx]] – Gp41 + Gp120 + antibody<br />
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**[[5hm1]] – Gp41 core + llama antibody <br />
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**[[6cdi]] – Gp41 + Gp120 + antibody – Cryo EM<br />
+
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**[[5u1f]], [[5thr]] – Gp41 + Gp120 + antibody + CD4<br />
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**[[5fyk]], [[5fyj]], [[4nco]] – Gp41 + Gp120 (mutant) + antibody<br />
+
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**[[5hm1]] – Gp41 + llama antibody <br />
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**[[3o3x]] – arGp41 - artificial<br />
**[[3o3x]] – arGp41 - artificial<br />
**[[4dzu]] – arGp41 + 3-α<br />
**[[4dzu]] – arGp41 + 3-α<br />

Revision as of 08:43, 17 July 2019

Core structure of acetylated gp41 from the HIV envelope glycoprotein, 1aik.

Drag the structure with the mouse to rotate

3D Structures of Gp41

Updated on 17-July-2019

References

  1. ↑ Chan DC, Kim PS. HIV entry and its inhibition. Cell. 1998 May 29;93(5):681-4. PMID:9630213
  2. ↑ Root MJ, Steger HK. HIV-1 gp41 as a target for viral entry inhibition. Curr Pharm Des. 2004;10(15):1805-25. PMID:15180542

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky

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