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5n9b
From Proteopedia
(Difference between revisions)
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==Crystal Structure of unliganded human IL-17RA== | ==Crystal Structure of unliganded human IL-17RA== | ||
| - | <StructureSection load='5n9b' size='340' side='right' caption='[[5n9b]], [[Resolution|resolution]] 1.90Å' scene=''> | + | <StructureSection load='5n9b' size='340' side='right'caption='[[5n9b]], [[Resolution|resolution]] 1.90Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[5n9b]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5N9B OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5N9B FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[5n9b]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5N9B OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5N9B FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5n92|5n92]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5n92|5n92]]</td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">IL17RA, IL17R ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5n9b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5n9b OCA], [http://pdbe.org/5n9b PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5n9b RCSB], [http://www.ebi.ac.uk/pdbsum/5n9b PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5n9b ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5n9b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5n9b OCA], [http://pdbe.org/5n9b PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5n9b RCSB], [http://www.ebi.ac.uk/pdbsum/5n9b PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5n9b ProSAT]</span></td></tr> | ||
</table> | </table> | ||
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== Function == | == Function == | ||
[[http://www.uniprot.org/uniprot/I17RA_HUMAN I17RA_HUMAN]] Receptor for IL17A, IL17F and, in dimer with IL17RE, for IL17C. Binds its IL17A ligand with low affinity, suggesting that additional components are involved in IL17A-induced signaling.<ref>PMID:21993848</ref> <ref>PMID:19838198</ref> | [[http://www.uniprot.org/uniprot/I17RA_HUMAN I17RA_HUMAN]] Receptor for IL17A, IL17F and, in dimer with IL17RE, for IL17C. Binds its IL17A ligand with low affinity, suggesting that additional components are involved in IL17A-induced signaling.<ref>PMID:21993848</ref> <ref>PMID:19838198</ref> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Interleukin receptor|Interleukin receptor]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Human]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Goepfert, A]] | [[Category: Goepfert, A]] | ||
[[Category: Rondeau, J M]] | [[Category: Rondeau, J M]] | ||
[[Category: Fibronectin type iii]] | [[Category: Fibronectin type iii]] | ||
[[Category: Signaling protein]] | [[Category: Signaling protein]] | ||
Revision as of 06:03, 12 June 2019
Crystal Structure of unliganded human IL-17RA
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