2eqy

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==Solution structure of the ARID domain of Jarid1b protein==
==Solution structure of the ARID domain of Jarid1b protein==
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<StructureSection load='2eqy' size='340' side='right' caption='[[2eqy]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
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<StructureSection load='2eqy' size='340' side='right'caption='[[2eqy]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2eqy]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EQY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2EQY FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2eqy]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EQY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2EQY FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Jarid1b ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Jarid1b ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2eqy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2eqy OCA], [http://pdbe.org/2eqy PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2eqy RCSB], [http://www.ebi.ac.uk/pdbsum/2eqy PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2eqy ProSAT], [http://www.topsan.org/Proteins/RSGI/2eqy TOPSAN]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2eqy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2eqy OCA], [https://pdbe.org/2eqy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2eqy RCSB], [https://www.ebi.ac.uk/pdbsum/2eqy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2eqy ProSAT], [https://www.topsan.org/Proteins/RSGI/2eqy TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/KDM5B_MOUSE KDM5B_MOUSE]] Histone demethylase that demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9' or H3 'Lys-27'. Demethylates trimethylated, dimethylated and monomethylated H3 'Lys-4'. Acts as a transcriptional corepressor for FOXG1B and PAX9.<ref>PMID:17320160</ref> <ref>PMID:17310255</ref>
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[[https://www.uniprot.org/uniprot/KDM5B_MOUSE KDM5B_MOUSE]] Histone demethylase that demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9' or H3 'Lys-27'. Demethylates trimethylated, dimethylated and monomethylated H3 'Lys-4'. Acts as a transcriptional corepressor for FOXG1B and PAX9.<ref>PMID:17320160</ref> <ref>PMID:17310255</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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==See Also==
==See Also==
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*[[Lysine-specific histone demethylase|Lysine-specific histone demethylase]]
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*[[Lysine-specific histone demethylase 3D structures|Lysine-specific histone demethylase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Large Structures]]
[[Category: Lk3 transgenic mice]]
[[Category: Lk3 transgenic mice]]
[[Category: Inoue, M]]
[[Category: Inoue, M]]

Revision as of 12:25, 10 February 2021

Solution structure of the ARID domain of Jarid1b protein

PDB ID 2eqy

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