2e5o
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
=='Solution structure of the TRIP_4C domain of target of activating signal cointegrator 1== | =='Solution structure of the TRIP_4C domain of target of activating signal cointegrator 1== | ||
| - | <StructureSection load='2e5o' size='340' side='right' caption='[[2e5o]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | + | <StructureSection load='2e5o' size='340' side='right'caption='[[2e5o]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2e5o]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2e5o]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E5O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2E5O FirstGlance]. <br> |
| - | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">TRIP4 ([ | + | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">TRIP4 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2e5o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2e5o OCA], [https://pdbe.org/2e5o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2e5o RCSB], [https://www.ebi.ac.uk/pdbsum/2e5o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2e5o ProSAT], [https://www.topsan.org/Proteins/RSGI/2e5o TOPSAN]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/TRIP4_HUMAN TRIP4_HUMAN]] Transcription coactivator of nuclear receptors which functions in conjunction with CBP-p300 and SRC-1 and may play an important role in establishing distinct coactivator complexes under different cellular conditions. Plays a pivotal role in the transactivation of NF-kappa-B, SRF and AP1. Acts as a mediator of transrepression between nuclear receptor and either AP1 or NF-kappa-B. Plays a role in androgen receptor transactivation and in testicular function (By similarity).<ref>PMID:12077347</ref> |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
| Line 24: | Line 24: | ||
</StructureSection> | </StructureSection> | ||
[[Category: Human]] | [[Category: Human]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Dang, W]] | [[Category: Dang, W]] | ||
[[Category: Inoue, M]] | [[Category: Inoue, M]] | ||
Revision as of 11:48, 10 February 2021
'Solution structure of the TRIP_4C domain of target of activating signal cointegrator 1
| |||||||||||
Categories: Human | Large Structures | Dang, W | Inoue, M | Kigawa, T | Muto, Y | Structural genomic | Shirouzu, M | Terada, T | Yokoyama, S | Activating signal cointegrator 1 | Asc-1 | National project on protein structural and functional analyse | Nppsfa | Rsgi | Thyroid receptor-interacting protein 4 | Transcription | Trip-4 | Trip4 c domain
