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6dg5
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Structure of a de novo designed Interleukin-2/Interleukin-15 mimetic complex with IL-2Rb and IL-2Rg== | |
| - | + | <StructureSection load='6dg5' size='340' side='right' caption='[[6dg5]], [[Resolution|resolution]] 2.52Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6dg5]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6DG5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6DG5 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr> | |
| - | [[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6dg5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6dg5 OCA], [http://pdbe.org/6dg5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6dg5 RCSB], [http://www.ebi.ac.uk/pdbsum/6dg5 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6dg5 ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/IL2RG_MOUSE IL2RG_MOUSE]] Common subunit for the receptors for a variety of interleukins. [[http://www.uniprot.org/uniprot/IL2RB_MOUSE IL2RB_MOUSE]] Receptor for interleukin-2. This beta subunit is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Baker, D]] | [[Category: Baker, D]] | ||
| - | [[Category: | + | [[Category: Garcia, K C]] |
| - | [[Category: Jude, K | + | [[Category: Jude, K M]] |
| - | [[Category: | + | [[Category: Silva, D A]] |
[[Category: Yu, S]] | [[Category: Yu, S]] | ||
| + | [[Category: Biosynthetic protein]] | ||
| + | [[Category: Biosynthetic protein-protein binding complex]] | ||
| + | [[Category: Cytokine mimetic]] | ||
| + | [[Category: Cytokine receptor complex]] | ||
Revision as of 12:06, 16 January 2019
Structure of a de novo designed Interleukin-2/Interleukin-15 mimetic complex with IL-2Rb and IL-2Rg
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