6dl7
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Human mitochondrial ClpP in complex with ONC201 (TIC10)== | |
| - | + | <StructureSection load='6dl7' size='340' side='right'caption='[[6dl7]], [[Resolution|resolution]] 2.00Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6dl7]] is a 7 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6DL7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6DL7 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ONC:7-benzyl-4-[(2-methylphenyl)methyl]-6,7,8,9-tetrahydroimidazo[1,2-a]pyrido[3,4-e]pyrimidin-5(4H)-one'>ONC</scene></td></tr> | |
| - | [[Category: | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Endopeptidase_Clp Endopeptidase Clp], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.92 3.4.21.92] </span></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6dl7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6dl7 OCA], [http://pdbe.org/6dl7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6dl7 RCSB], [http://www.ebi.ac.uk/pdbsum/6dl7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6dl7 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/CLPP_HUMAN CLPP_HUMAN]] Clp cleaves peptides in various proteins in a process that requires ATP hydrolysis. Clp may be responsible for a fairly general and central housekeeping function rather than for the degradation of specific substrates. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Endopeptidase Clp]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Halgas, O]] | ||
| + | [[Category: Pai, E F]] | ||
| + | [[Category: Schimmer, A]] | ||
| + | [[Category: Zarabi, S F]] | ||
| + | [[Category: Degradation]] | ||
| + | [[Category: Homeostasis]] | ||
| + | [[Category: Hydrolase]] | ||
| + | [[Category: Mitochondria]] | ||
| + | [[Category: Protease]] | ||
Revision as of 11:15, 10 May 2019
Human mitochondrial ClpP in complex with ONC201 (TIC10)
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